Publications de Christos Sourmpis

Capturing behavioral and neural variability in multi-area spiking neuronal network models

How does the brain generate behavioral responses from sensory stimuli? This sensor-to-motor transformation is a fundamental question in systems neuroscience. While recent experiments have highlighted the complexity of neural representations across the cere ...

EPFL2025

Auditory stimuli suppress contextual fear responses in safety learning independent of a possible safety meaning

Ralf Schneggenburger, Olexiy Kochubey, Johanni Michael Brea, Christos Sourmpis, Denys Osypenko, Shriya Palchaudhuri

Safety learning allows the identification of non-threatening situations, a learning process instrumental for survival and psychic health. In contrast to fear learning, in which a sensory cue (conditioned stimulus, CS) is temporally linked to a mildly avers ...

2024

Striatal Dopamine Signals and Reward Learning

Carl Petersen, Sylvain Crochet, Parviz Ghaderi, Mauro Pulin, Anthony Pierre Robert Renard, Christos Sourmpis, Pol Bech Vilaseca, Meriam Malekzadeh, Robin François Virginien Dard, Yanqi Liu

We are constantly bombarded by sensory information and constantly making decisions on how to act. In order to optimally adapt behavior, we must judge which sequences of sensory inputs and actions lead to successful outcomes in specific circumstances. Neuro ...

Oxford Univ Press2023

Distributed and specific encoding of sensory, motor, and decision information in the mouse neocortex during goal-directed behavior

Wulfram Gerstner, Carl Petersen, Sylvain Crochet, Alireza Modirshanechi, Vahid Esmaeili, Christos Sourmpis, Anastasiia Oryshchuk

Goal-directed behaviors involve coordinated activity in many cortical areas, but whether the encoding of task variables is distributed across areas or is more specifically represented in distinct areas remains unclear. Here, we compared representations of ...

Cell Press2023