Publications de Eduard Vico Oton

Bile acid 7α-dehydroxylating bacteria accelerate injury-induced mucosal healing in the colon

Kristina Schoonjans, Rizlan Bernier-Latmani, Alessia Perino, Hadrien Charles Edouard Demagny, Eduard Vico Oton, Colin Volet, Antoine Jalil

Host-microbiome communication is frequently perturbed in gut pathologies due to microbiome dysbiosis, leading to altered production of bacterial metabolites. Among these, 7 alpha-dehydroxylated bile acids are notably diminished in inflammatory bowel diseas ...

SPRINGERNATURE2025

Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

Eduard Vico Oton

Pseudomonas aeruginosa is one of the top priority pathogens that requires immediate attention according to the World Health Organisation (WHO). Due to the alarming shortage of novel antimicrobials, targeting quorum sensing (QS), a bacterial cell to cell si ...

2024

BaiJ and BaiB are key enzymes in the chenodeoxycholic acid 7a-dehydroxylation pathway in the gut microbe Clostridium scindens ATCC 35704

Rizlan Bernier-Latmani, Laure Menin, Karin Lederballe Meibom, Eduard Vico Oton, Théo Nass, Colin Volet, Solenne Anne Marie Marion

Bile acid transformation is a common gut microbiome activity that produces secondary bile acids, some of which are important for human health. One such process, 7α-dehydroxylation, converts the primary bile acids, cholic acid and chenodeoxycholic acid, to ...

2024

Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid

Rizlan Bernier-Latmani, Karin Lederballe Meibom, Nicolas Louis Maurice Jacquemin, Eduard Vico Oton, Colin Volet

Springer Science and Business Media LLC2024

Impacts of diffuse urban stressors on stream benthic communities and ecosystem functioning: A review

Eduard Vico Oton

Catchment urbanisation results in urban streams being exposed to a multitude of stressors. Notably, stressors originating from diffuse sources have received less attention than stressors originating from point sources. Here, advances related to diffuse urb ...

2024