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Ghislain Gilles Jean-Michel Motos

Publications associées (12)

Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria

Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler, Htet Kyi Wynn, Céline Terrettaz, Laura José Costa Henriques, Daniel Scott Nolan, Marta Augugliaro

Aerosol transmission remains a major challenge for control of respiratory viruses, particularly those causing recurrent epidemics, like influenza A virus (IAV). These viruses are rarely expelled alone, but instead are embedded in a consortium of microorgan ...
2024

Inactivation mechanisms of influenza A virus under pH conditions encountered in aerosol particles as revealed by whole-virus HDX-MS

Athanasios Nenes, Tamar Kohn, Giovanni D'Angelo, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler, Jonathan Paz Montoya

Multiple respiratory viruses, including influenza A virus (IAV), can be transmitted via expiratory aerosol particles, and aerosol pH was recently identified as a major factor influencing airborne virus infectivity. Indoors, small exhaled aerosols undergo r ...
2023

The neuraminidase activity of influenza A virus determines the strain-specific sensitivity to neutralization by respiratory mucus

Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler

Respiratory mucus lining the airway epithelium constitutes an important first line of defense against infection with influenza A virus (IAV). Previous studies suggested that the inhibitory potential of mucus relies not only on the presence of decoy recepto ...
2023

Salt-mediated inactivation of influenza A virus in 1- μl droplets exhibits exponential dependence on NaCl molality

Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler, Céline Terrettaz, Laura Costa, Laura José Costa Henriques

Influenza A virus (IAV) spreads through airborne particles ranging from sub-micrometer to millimeter-sized droplets. The stability of airborne IAV remains difficult to estimate and depends, among others, on the respiratory matrix composition and the size-d ...
2023

Physicochemical characterization and source apportionment of Arctic ice-nucleating particles observed in Ny-Alesund in autumn 2019

Athanasios Nenes, Ghislain Gilles Jean-Michel Motos, Jörg Wieder, Guangyu Li

Ice-nucleating particles (INPs) initiate primary ice formation in Arctic mixed-phase clouds (MPCs), altering cloud radiative properties and modulating precipitation. For atmospheric INPs, the complexity of their spatiotemporal variations, heterogeneous sou ...
Gottingen2023

Aerosol and dynamical contributions to cloud droplet formation in Arctic low-level clouds

Athanasios Nenes, Ghislain Gilles Jean-Michel Motos, Paraskevi Georgakaki, Jörg Wieder, Guangyu Li

The Arctic is one of the most rapidly warming regions of the globe. Low-level clouds and fog modify the energy transfer from and to space and play a key role in the observed strong Arctic surface warming, a phenomenon commonly termed "Arctic amplification" ...
Gottingen2023

Expiratory Aerosol pH: The Overlooked Driver of Airborne Virus Inactivation

Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler

Respiratory viruses, including influenza virus and SARS-CoV-2, are transmitted by the airborne route. Air filtration and ventilation mechanically reduce the concentration of airborne viruses and are necessary tools for disease mitigation. However, they ign ...
2022

Inactivation mechanisms of influenza A virus within the micro-environment of expiratory bioaerosols

Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler

Approximately 400’000 deaths are associated with influenza virus every year. Whilst currently dwarfed by the COVID-19 pandemic, influenza continues to circulate within the human population since the first recorded 1918 pandemic over a century ago. During t ...
2022

In-situ observations of aerosol-cloud interactions in Ny-Ålesund, Svalbard, during fall 2019 and spring 2020

Athanasios Nenes, Ghislain Gilles Jean-Michel Motos, Paraskevi Georgakaki, Jörg Wieder

The Arctic region suffers an extreme vulnerability to climate change, with an increase in surface air temperatures that have reached twice the global rate during several decades (McBean et al., 2005). The role of clouds, and in particular low-levels clouds ...
2021

In-Situ Observations Of Aerosol Hygroscopicity And Cloud Droplet Formation In Ny-Ålesund, Svalbard, During Fall 2019 And Spring 2020

Athanasios Nenes, Ghislain Gilles Jean-Michel Motos, Paraskevi Georgakaki, Jörg Wieder

The Arctic region suffers an extreme vulnerability to climate change, with an increase in surface air temperatures that have reached twice the global rate during several decades (McBean et al., 2005). The role of clouds, and in particular low-levels clouds ...
2021

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