Publications de Pierre Gérard Joseph Palamini

Radical-Mediated Azidation of Benzylic C-H Bonds and Azidofunctionalization of Alkenes

Organic azides are known for their reactivity and broad applicability in organic synthesis. These compounds are pivotal in various chemical transformations, including nucleophilic substitution and cycloaddition reactions. Beyond synthetic chemistry, organi ...

EPFL2025

The Azidofunctionalization of Alkenes

Jérôme Waser, Pierre Gérard Joseph Palamini

The azidofunctionalization of alkenes has emerged as a powerful difunctionalization strategy, expanding the toolbox of synthetic chemistry. This transformation enables the simultaneous installation of an azide and a second functional group onto an alkene, ...

Wiley2025

Photocatalyzed Azidofunctionalization of Alkenes via Radical-Polar Crossover

Jérôme Waser, Pierre Gérard Joseph Palamini, Alexandre Alain Schöpfer

The azidofunctionalization of alkenes under mild conditions using commercially available starting materials and easily accessible reagents is reported based on a radical-polar crossover strategy. A broad range of alkenes, including vinyl arenes, enamides, ...

Wiley2025

Benzylic C(sp3)-H Azidation: Copper vs Iron Catalysis

Qian Wang, Jieping Zhu, Jérôme Waser, Pierre Gérard Joseph Palamini, Raphaël Michel Henri Simonet-Davin

The generation of benzylic radicals through hydrogen atom abstraction (HAT) has been a recent research focus and various C(sp(3))-H bond functionalization protocols have been developed relying on this elementary step. We report herein copper- and iron-cata ...

2024

Acyl-Ethynylbenziodoxolone (acyl-EBX): Access to Ketene Dithioarylacetals

Jérôme Waser, Pierre Gérard Joseph Palamini, Morgane Elodie Marie Delattre, Julien Aymeric Borrel, Maël Djaïd

We report the synthesis of ketene dithioarylacetals in 40–97% yield using thiophenols and acyl-EBXs (ethynylbenziodoxolones) generated in situ from a common hypervalent iodine precursor and alkynyl trifluoroborate salts. The products could be further modif ...

2023

Iron-Catalyzed Synthesis of α-Azido α-Amino Esters via the Alkylazidation of Alkenes

Jérôme Waser, Pierre Gérard Joseph Palamini, Emmanuelle Madeline Dominique Allouche

2023

Raw data for article "Iron-catalyzed synthesis of α-azido α-amino esters via the alkylazidation of alkenes"

Jérôme Waser, Pierre Gérard Joseph Palamini, Emmanuelle Madeline Dominique Allouche

Raw NMR, IR and MS data for the article "Iron-catalyzed synthesis of α-azido α-amino esters via alkylazidation of alkenes" published in Org. Lett. The number of the folders either correspond to compounds numbers in the article or the name of the folder is ...

Zenodo2023