Privacy in the Genomic Era

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The Privacy Power of Correlated Noise in Decentralized Learning

Rachid Guerraoui, Martin Jaggi, Youssef Allouah, Anastasiia Koloskova, Aymane El Firdoussi

Decentralized learning is appealing as it enables the scalable usage of large amounts of distributed data and resources (without resorting to any central entity), while promoting privacy since every user minimizes the direct exposure of their data. Yet, wi ...

PMLR2024

Reconstruction and analysis of genome-scale metabolic networks in single organisms and microbial communities

Evangelia Vagena

Microorganisms are a key component in the chain of life. They are essential for agriculture, produce a large proportion of oxygen, and play a central role in the cycle of elements. Microorganisms are widely used in the production of food and alcoholic beve ...

EPFL2024

Microbial genome collection of aerobic granular sludge cultivated in sequencing batch reactors using different carbon source mixtures

Christof Holliger, Aline Sondra Adler, Laetitia Janine Andrée Cardona, Jaspreet Singh Saini, Pilar Natalia Rodilla Ramírez, Ruizhe Pei

Aerobic granular sludge (AGS) consists of a microbial consortium that has an important role in wastewater treatment. This study investigates AGS microorganisms cultivated in a laboratory-scale sequencing batch reactor. Metagenomic sequencing was conducted ...

Amer Soc Microbiology2024

PRO-Face C: Privacy-Preserving Recognition of Obfuscated Face via Feature Compensation

Touradj Ebrahimi, Lin Yuan, Xiao Pu, Yao Zhang, Hongbo Li

The advancement of face recognition technology has delivered substantial societal advantages. However, it has also raised global privacy concerns due to the ubiquitous collection and potential misuse of individuals' facial data. This presents a notable par ...

Ieee-Inst Electrical Electronics Engineers Inc2024

Privacy-Preserving Machine Learning on Graphs

Sina Sajadmanesh

Graph Neural Networks (GNNs) have emerged as a powerful tool for learning on graphs, demonstrating exceptional performance in various domains. However, as GNNs become increasingly popular, new challenges arise. One of the most pressing is the need to ensur ...

EPFL2023

Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E

Jacques Fellay

Background and Aims:The clinical spectrum of human infection by HEV ranges from asymptomatic to severe acute hepatitis. Furthermore, HEV can cause diverse neurological manifestations, especially Parsonage-Turner syndrome. Here, we used a large-scale human ...

Lippincott Williams & Wilkins2023

Development of multiplexed single-molecule imaging techniques to study chromatin invasion dynamics of chromatin effector proteins

Kristina Makasheva

DNA-binding proteins physically interact with the DNA and directly affect genomic functions. The eukaryotic genome is compacted into chromatin, limiting the DNA access to nuclear factors. In this Ph.D. thesis, I explored the dynamic mechanisms, that allow ...

EPFL2023

Sulfurospirillum diekertiae sp. nov., a tetrachloroethene-respiring bacterium isolated from contaminated soil

Christof Holliger, Julien Maillard, Junxiong Wang

Two anaerobic, tetrachloroethene- (PCE-) respiring bacterial isolates, designated strain ACSDCE T and strain ACSTCE, were characterized using a polyphasic approach. Cells were Gram-stain-negative, motile, non-spore-forming and shared a vibrioid- to spirill ...

2023

Landscapes of DNA Mechanics and Genomes

Thomas Antonin Zwahlen

The local physical properties - such as shape and flexibility - of the DNA double-helix is today widely believed to be influenced by nucleic acid sequence in a non-trivial way. Furthermore, there is strong evidence that these properties play a role in many ...

EPFL2023

Bridging the gap between theoretical and practical privacy technologies for at-risk populations

Kasra Edalatnejadkhamene

With the pervasive digitalization of modern life, we benefit from efficient access to information and services. Yet, this digitalization poses severe privacy challenges, especially for special-needs individuals. Beyond being a fundamental human right, priv ...

EPFL2023

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