Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept

Hilal Lashuel, Adrian Schmid, Richard Alan Mimna, Marie-Stéphanie Camus
2007
Article

Résumé

Reversal of amyloid formation through a controlled induced transformation from beta-sheet to sol. alpha-helix structures through the use of a switch element S could have an important consequences understanding the mechanisms of amyloid formation and clearance.

Source officielle

https://infoscience.epfl.ch/record/109862?ln=fr

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Disruption of amyloid-derived peptide assemblies through the controlled induction of a beta-sheet to alpha-helix transformation: application of the switch concept

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