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Physical properties and interactions of biomolecules

Publications associées (62)

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Force spectroscopy of barnase-barstar single molecule interaction

Giovanni Dietler, Mélanie Favre, Dmitry Klinov

Results of the single molecule force spectroscopy study of specific interactions between ribonuclease barnase and its inhibitor barstar are presented. Experimental data obtained for the force loading rate ranging 2-70 nN/s are well approximated by a single ...

Wiley-Blackwell2010

DNA Topology

Guillaume Witz

This thesis explores different aspects of DNA topology through experimental and numerical techniques. Topology is a vast mathematical field, that deals with the spatial properties of objects undergoing continuous deformations, but here it is restricted to ...

EPFL2010

Fluctuations of the Casimir-like force between two membrane inclusions

Anne-Florence Raphaëlle Bitbol

Although Casimir forces are inseparable from their fluctuations, little is known about these fluctuations in soft matter systems. We use the membrane stress tensor to study the fluctuations of the membrane-mediated Casimir-like force. This method enables u ...

American Physical Society (APS)2010

Monitoring ligand–receptor interactions by photonic force microscopy

László Forró, Flavio Maurizio Mor, Sylvia Jeney

We introduce a method for the acquisition of single molecule force measurements of ligand-receptor interactions using the photonic force microscope (PFM). Biotin-functionalized beads, manipulated with an optical trap, and a streptavidin-functionalized cove ...

Institute of Physics2010

Magnetism of individual atoms adsorbed on surfaces

Harald Brune, Pietro Gambardella

Magnetic impurities in solids cause manifold changes in their macroscopic properties, such as anomalous low temperature resistance due to Kondo screening, reduction of the superconducting transition temperature due to local suppression of the order paramet ...

Elsevier2009

Biological samples studied by optical nanospectroscopy

Johanna Generosi

The different parts of the electromagnetic spectrum result in diverse effects upon interaction with matter: according to the wavelength, the radiation has energy appropriate for the excitation of a specific physical process. X-rays can be used as a tool to ...

EPFL2009

Detection of buried microstructures by nonlinear light scattering spectroscopy

Sylvie Roke, Hilton Barbosa De Aguiar

Many processes in chemistry and physics rely on the structure, growth or change of material buried in solids. The impenetrable surrounding medium often prohibits the study of such material in situ. Nonlinear light scattering can be used to observe the inte ...

2009

Development of a 2-DOF Electrostatic Haptic Joystick for MRI/fMRI Applications

This paper describes the development of a 2-DOF electrostatic haptic joystick designed for neuroscience studies in an MRI/fMRI. The joystick is fabricated using non-magnetic materials and actuated by two high-power electrostatic motor units which produce v ...

2009

Scaling of double and single stranded DNA

Giovanni Dietler

Long double stranded DNA (DsDNA) and single stranded DNA (ssDNA) molecules were studied by direct imaging with the Atomic Force Microscope (AFM) in order to determine their scaling properties, exponents, distributions and persistence length in the frame wo ...

2009

Theoretical Model of Polymer Plasma Laser Ablation

Maria-Alexandra Paun

Polymer plasma laser ablation has been investigated theoretically. An elegant mathematical tool using the fractal structure of space-time was developed. The model was verified with good accuracy on the existing experimental results. ...

2009