Physical properties and interactions of biomolecules
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‘Real-time’ nanoscale imaging and single molecule force spectroscopy of bio-chemical specimen based on atomic force microscopy (AFM) requires cantilevers with both low force constant and high-resonant frequency. The required spring constant should be betwe ...
The main purpose of this thesis is to explore a new concept of SNOM probes. In order to produce more reliable and reproducible tips, we propose to graft a single gold particle of 60 nm diameter onto the aperture of a SNOM probe. The expected advantage of s ...
Tendons are composed of collagen and other molecules in a highly organized hierarchical assembly, leading to extraordinary mechanical properties. To probe the cross-links on the lower level of organization, we used a cantilever to pull substructures out of ...
AFM-based single molecule force spectroscopy has developed into a standard method to gain information about molecular elasticities, internal structural transitions and binding forces and kinetics of single (bio-)+molecules. The sensitivity and the resoluti ...
Bilateral Master-Slave force reflecting servomechanisms are very interesting and useful devices. The basic principle of these systems is too realise a force and position transformation between the two mechanisms. This paper presents the design of the multi ...
The molecular processes based on the specific receptor-ligand interactions (e.g. immune response to a foreign antigen, communication between nerve cells, etc.) are essential for a good and stable performance of living organisms. The aim of the present work ...
The advent of scanning near-field optical microscopy (SNOM) has augmented at a microscopic level the usefulness of optical spectroscopy in the region between 300 nm and 10 mum. Two-dimensional imaging of chemical constituents makes this a very attractive a ...
A family of cationic polyelectrolytes possessing defined chain lengths, narrow chain length distributions, uniform charge d., but substituents of different hydrophilicity at the quaternary ammonium group served as model compds. for adsorption studies. Thes ...
We present an experimental and theoretical investigation into time- vs. frequency-domain femtosecond sum frequency spectroscopy at the metal-liquid interface. Although frequency and time-domain measurements are theoretically equivalent it is demonstrated h ...
Atomic force microscopy (AFM) force-distance curves have become a fundamental tool in several fields of research, such as surface science, materials engineering, biochemistry and biology. Furthermore, they have great importance for the study of surface int ...
