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Highly efficient MRI contrast agents

Publications associées (76)

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Functionalization of harmonic nanoparticles for drug release and multimodal imaging applications

Adrian Stefan Gheata

Cancer is among the leading causes of death worldwide, and as knowledge of the disease continues to grow there is an increasing interest towards precision medicine: more specifically towards the theranostics field, i.e the development of targeted molecular ...

EPFL2024

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Dichalcogenolenes are archetypal redox non-innocent ligands with numerous applications. Herein, we describe a diselenolene ligand with fundamentally different electronic properties. By selenation of a C2-protected imidazolium salt, we have prepared a mesoi ...

2022

Fast and Sensitive Detection of Paramagnetic Species Using Coupled Charge and Spin Dynamics in Strongly Fluorescent Nanodiamonds

Sensing of a few unpaired electron spins, such as in metal ions and radicals, is a useful but difficult task in nanoscale physics, biology, and chemistry. Single negatively charged nitrogen-vacancy (NV-) centers in diamond offer high sensitivity and spatia ...

2019

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Despite extensive advances in the field of molecular recognition, the real-time monitoring of small molecule binding to nanoparticles (NP) remains a challenge. To this end, we report on a versatile approach, based on quartz crystal microbalance with dissip ...

ROYAL SOC CHEMISTRY2019

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Molecular uranium nitride complexes were prepared to relate their small molecule reactivity to the nature of the U & xe001;N & xe001;U bonding imposed by the supporting ligand. The U4+-U4+ nitride complexes, [NBu4][{(((BuO)-Bu-t)(3)SiO)(3)U}(2)(mu-N)], [NB ...

2019

Here we show that it is possible to produce different magnetic core multiple shell heterostructures from monodisperse Fe3O4 spherical magnetic seeds by finely controlling the amount of a manganese precursor and using, in a smart and simple way, a cation-ex ...

Amer Chemical Soc2017

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Due to their high chemical affinity towards metal ions, chelating agents (CAs) have been used for decades for water purification, but also for protection against metal intoxication and in nanomedicine as linking molecules at the surface of nanoparticles. H ...

RSC Publishing2017

Superparamagnetic Nanoparticles as High Efficiency Magnetic Resonance Imaging T-2 Contrast Agent

Henrik Moodysson Rønnow, Francesco Stellacci, Kurt Schenk, Paulo Henrique Jacob Silva, Lin Yang, Randy Patrick Carney, Ping Huang, Arash Alahgholipour Omrani, Tamara Michael Carney

Nanoparticle-based magnetic resonance imaging T-2 negative agents are of great interest, and much effort is devoted to increasing cell loading capability while maintaining low cytotoxicity. Herein, two classes of mixed-ligand protected magnetic-responsive, ...

American Chemical Society2017

Recent Advances in the Synthesis and Applications of Multimodal Gold-Iron Nanoparticles

Francesco Stellacci

Bimetallic particles based on gold and iron have been gathering increasing interest in biomedical applications because of the synergic combination of the plasmonic features of the inert gold component with the magnetic properties of the iron or iron oxide ...

Bentham Science Publishers2017

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Gadolinium‐loaded nanomicelles show promise as future magnetic resonance imaging (MRI) contrast agents (CAs). Their increased size and high gadolinium (Gd) loading gives them an edge in proton relaxivity over smaller molecular Gd‐complexes. Their size and ...

2017