Publication
Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models
Publications associées (52)
Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin
Polymorphonuclear neutrophils contain at least four serine endopeptidases, namely neutrophil elastase (NE), proteinase 3 (PR3), cathepsin G (CatG), and NSP4, which contribute to the regulation of infection and of inflammatory processes. In physiological co ...
2020Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly
Tristan Bolmont, Taoufiq Harach
The pathway leading from amyloid-b deposition to cognitive impairment is believed to be a cornerstone of the pathogenesis of Alzheimer's disease (AD). However, what drives amyloid buildup in sporadic nongenetic cases of AD is still unknown. AD brains featu ...
Elsevier Science Inc2017Synergistic effect of carboxylic and amine ligands on the synthesis of CdSe nanocrystals
Martinus Gijs, Virendra Kumar Parashar
We demonstrate the drastic improvement in absorbance and photoluminescence (UV-PL) of CdSe nanocrystals (NCs) upon adding both a carboxylic acid and an amine ligand to the cadmium acetate green chemistry source. We combined carboxylate complexes of lauric ...
Royal Soc Chemistry2016LRH-1 mediates anti-inflammatory and antifungal phenotype of IL-13-activated macrophages through the PPAR gamma ligand synthesis
Kristina Schoonjans, Matthias Alexander Sokrates Stein
Liver receptor homologue-1 (LRH-1) is a nuclear receptor involved in the repression of inflammatory processes in the hepatointestinal tract. Here we report that LRH-1 is expressed in macrophages and induced by the Th2 cytokine IL-13 via a mechanism involvi ...
Nature Publishing Group2015The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation
Jacques Rougemont, Laure Menin, Nicola Harris, Alessandra Piersigilli, Benjamin John Marsland, Mario Michael Zaiss, Ilaria Mosconi, Lalit Kumar Dubey, Alexis Rapin, Luc Xavier Marie Lebon, Andrew J. Macpherson
Intestinal helminths are potent regulators of their host's immune system and can ameliorate inflammatory diseases such as allergic asthma. In the present study we have assessed whether this anti-inflammatory activity was purely intrinsic to helminths, or w ...
Elsevier2015Growth and dissolution of calcite in the presence of adsorbed stearic acid
Francesco Stellacci, Georg Fantner, Kislon Voitchovsky, Blake William Erickson, Maria Ricci, Juan José Segura Sugranes
The interaction of organic molecules with the surface of calcite plays a central role in many geochemical, petrochemical and industrial processes and in biomineralization. Adsorbed organics, typically fatty acids, can interfere with the evolution of calcit ...
American Chemical Society2015Thymic stromal lymphopoietin plays divergent roles in murine models of atopic and nonatopic airway inflammation
Nicola Harris, Benjamin John Marsland, Ilaria Mosconi
BackgroundThymic stromal lymphopoietin (TSLP) is a cytokine primarily produced by epithelial cells, which has been shown to be a potent inducer of T-helper 2 (Th2)-type responses. However, TSLP has pleiotropic effects upon immune cells, and although extens ...
Wiley-Blackwell2014NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids
Macrophage-mediated inflammation is a major contributor to obesity-associated insulin resistance. The corepressor NCoR interacts with inflammatory pathway genes in macrophages, suggesting that its removal would result in increased activity of inflammatory ...
Cell Press2013Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages
Arne Seitz, Romain Guiet, Nicola Harris, Alessandra Piersigilli, Beatrice Volpe, Julia Esser-von Bieren, Ilaria Mosconi, Fei Chen
Approximately one-third of the world's population suffers from chronic helminth infections with no effective vaccines currently available. Antibodies and alternatively activated macrophages (AAM) form crucial components of protective immunity against chall ...
Public Library of Science2013Selective in vivo visualization of immune-cell infiltration in a mouse model of autoimmune myocarditis by fluorine-19 cardiac magnetic resonance
Background- The goal of this study was to characterize the performance of fluorine-19 ((19)F) cardiac magnetic resonance (CMR) for the specific detection of inflammatory cells in a mouse model of myocarditis. Intravenously administered perfluorocarbons are ...
2013