A microelectrode array (MEA) integrated with clustering structures for investigating in vitro neurodynamics in confined interconnected sub-populations of neurons
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A 100-channel fully implantable wireless broadband neural recording system was developed. It features 100 parallel broadband (0.1 Hz-7.8 kHz) neural recording channels, a medical grade 200 mAh Li-ion battery recharged inductively at 150 kHz, and data telem ...
Neuronal firing, synaptic transmission, and its plasticity form the building blocks for processing and storage of information in the brain. It is unknown whether adult human synapses are more efficient in transferring information between neurons than roden ...
The organization of connectivity in neuronal networks is fundamental to understanding the activity and function of neural networks and information processing in the brain. Recent studies show that the neocortex is not only organized in columns and layers b ...
Neocortex, the neuronal structure at the base of the remarkable cognitive skills of mammals, is a layered sheet of neuronal tissue composed of juxtaposed and interconnected columns. A cortical column is considered the basic module of cortical processing pr ...
A key issue toward the realization of retinal prosthetic devices is a reliable transduction of the information carried by light into specific patterns of electrical activity at the level of the networks involved in visual information processing. In this pe ...
Since the seminal work of Watts in the late 90s, graph-theoretic analyses have been performed on many complex dynamic networks, including brain structures. Most studies have focused on functional connectivity defined between whole brain regions, using imag ...
An important feature of the nervous system is its ability to adapt to new stimuli. This adaptation allows for optimal encoding of the incoming information by dynamically changing the coding strategy based upon the incoming inputs to the neuron. At the leve ...
Since the seminal work of Watts & Strogatz and others in the late 90s [1], graph-theoretic analyses have been performed on many complex dynamic networks, including brain structures. Most studies have focused on functional connectivity defined between whole ...
The present invention relates to methods and neuronal cellular preparations allowing monitoring intracellular and transcellular molecular events on both short and long timescales in an ex vivo neuronal network of intact post-mitotic neurons. In particular, ...
Interfacing artificial functional materials and living neuronal tissues is at the forefront of bio-nanotechnology. Attempts so far have been based on microscope processing of metals, inorganic semiconductors as electrodes or photoactive layers in biased de ...
