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Electrokinetically driven microfluidic chips with surface-modified chambers for heterogeneous immunoassays

Publications associées (71)

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Selective Trapping of DNA Using Glass Microcapillaries

Nadanai Laohakunakorn

We show experimentally that an inexpensive glass microcapillary can accumulate lambda-phage DNA at its tip and deliver the DNA into the capillary using a combination of electro-osmotic flow, pressure-driven flow, and electrophoresis. We develop an efficien ...

American Chemical Society2016

Development of a microfluidic interface for suspended microchannel resonators

Damien Maillard

Suspended microchannel resonators (SMRs) are devices that detect particles in liquid samples. In comparison with similar resonating devices that must be immersed, SMRs allow the fluids to flow through microfluidic resonators. This principle of operation le ...

2016

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Magnetic micro-and nanoparticles ('magnetic beads') have been used to advantage in many microfluidic devices for sensitive antigen (Ag) detection. Today, assays that use as read-out of the signal the number count of immobilized beads on a surface for quant ...

Elsevier2015

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Aims: Here we report a one-step approach for reproducible synthesis of finely tuned targeting multifunctional hybrid nanoparticles (HNPs). Materials & methods: A microfluidic-assisted method was employed for controlled nanoprecipitation of bisphosphonate-c ...

Future Medicine Ltd2015

It is in the context of miniaturization that arises the microfluidics concept. It is not uncommon in chemical, biological or medical analysis laboratories to manipulate or to mix fluids while measuring the results with filters, spectrometers or all other e ...

EPFL2014

PowerCool: Simulation of Integrated Microfluidic Power Generation in Bright Silicon MPSoCs

David Atienza Alonso, Arvind Raj Mahankali Sridhar, Bruno Michel

Integrated microfluidic power generation and power delivery promises to be a disruptive packaging technology with the potential to combat dark silicon. It essentially consists of integrated microchannel-based electrochemical “flow cells” in a 2D/3D multipr ...

IEEE/ACM Press2014

Programmable parylene-C bonding layer fluorescence for storing information on microfluidic chips

Martinus Gijs, Diego Gabriel Dupouy, Ata Tuna Ciftlik

We demonstrate data storage on glass/silicon microfluidic devices fabricated using parylene-C as a bonding layer. In particular, we report intermediate parylene-C bonding layer fluorescence (iPBLF) and its use as an on-chip medium for data storage by dynam ...

Royal Society of Chemistry2013

Sample processing device with detachable slide

Martinus Gijs, Ata Tuna Ciftlik

A biological and chemical sample processing device that b. comprises a high pressure-resistant, shallow and wide area microfluidic chamber having at least one wall formed by a detachable slide containing samples such as immobilized entities, biological sam ...

2013

Development of Elastomeric Optofluidic Devices for Lasing and Sensing

Wuzhou Song

The term of optofluidics defines an emergent research field that combines microfluidics and optics. In many lab-on-a-chip applications, these two technologies are used in combining the microfluidics for sample delivery and optics for sensing and controllin ...

EPFL2012

Automated Analysis of Rare Biomarkers Using a Magnetic Bead Surface Coverage Assay Coupled with Chaotic Mixing on a Microfluidic Chip

Hüseyin Cumhur Tekin

Extremely sensitive protein detection is crucial for early diagnosis and monitoring of diseases. Present day’s limit of detection for an antibody-antigen recognition-based immunoassay in serum without having to use special target antigen amplification tech ...

EPFL2012