Efficient oxygen transfer by surface aeration in shaken cylindrical containers for mammalian cell cultivation at volumetric scales up to 1,000 liters
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Driven by the commercial success of recombinant biopharmaceuticals, there is an increasing demand for novel, cost-effective mammalian cell culture bioreactor systems for the production of biologicals requiring mammalian protein processing. Recently, orbita ...
This paper presents a Lagrangian approach for the simulation of two-dimensional free-surface flows along with a systematic validation. Fluid-flow is traditionally modeled using an Eulerian description in association with finite differences and, more recent ...
River and open-channel flows are free surface boundary layer flows with complex 3D, large-scale, turbulent structures. The study of 2D and 3D large-scale turbulent flow structures is a great challenge for physicists, mathematicians and engineers from such ...
This paper presents a review of the mathematical models which can be adopted to describe the different physical phenomena characterizing the flow around a sailing yacht. The complete model accounting for laminar-turbulent transition regime, free-surface dy ...
The core of this modelling is to study heat transfer and fluid dynamics processes for a compression expansion system, and the main particularity is that heat transfer and air movement are due to the movement of the piston. We have implemented a "moving mes ...
The research work reported in the present dissertation is aimed at the analysis of complex physical phenomena involving instabilities and nonlinearities occurring in fluids through state-of-the-art numerical modeling. Solutions of intricate fluid physics p ...
The flow after the rupture of a dam on an inclined plane of arbitrary slope, and the induced transport of non-cohesive sediment, is analysed using the shallow-water approximation. An asymptotic (analytical) solution is presented for the flow hydrodynamics, ...
Microreactor technology, an important method of process intensification, offers numerous potential benefits for the process industries. Fluid–fluid reactions with mass transfer limitations have already been advantageously carried out in small-scale geometr ...
We present a discontinuous Galerkin method on a fully unstructured grid for the modeling of unsteady incompressible fluid flows with free surfaces. The surface is modeled by embedding and represented by a level set. We discuss the discretization of the flo ...
With increasing computer capabilities, numerical modeling of two-phase flows has developed significantly over the last few years. Although there are two main categories, namely 'one' fluid and 'two' fluid methods, the 'one' fluid methods are more commonly ...
