in vivo Electrical Impedance Spectroscopy of Tissue Reaction to Microelectrode Arrays
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Abstract: Recent advances in brain-machine interfaces (BMIs) have demonstrated the possibility of motor neuroprosthetics directly controlled by brain activity. Ideally neuroprosthetic limbs should be integrated in the body schema of the subject. To explore ...
Redundant encoding of information facilitates reliable distributed information processing. To explore this hypothesis in the motor system, we applied concepts from information theory to quantify the redundancy of movement-related information encoded in the ...
Brain–machine interfaces1, 2 use neuronal activity recorded from the brain to establish direct communication with external actuators, such as prosthetic arms. It is hoped that brain–machine interfaces can be used to restore the normal sensorimotor function ...
Information encoded in neuron ensembles has previously been hypothesized to be highly redundant, despite the apparent inefficiency of a redundant encoding system. The recent availability of intracortical, multi-electrode recordings has enabled the possibil ...
Interactions among neurons can take place in a wide variety of forms. It is the goal of this thesis to investigate the properties and implications of a number of these interactions that we believe are relevant for information processing in the brain. Neuro ...
Recently, CMOS-based microelectrode arrays containing a high-density of electrodes have emerged as a tool enabling recording the extracellular neural electrical activity of cell cultures at subcellular resolution. However, several improvements in areas suc ...
A preferred frequency is identified, being usable to stimulate a neurological target within a mammalian body using at least one microelectrode positioned at or near the target. To establish efficient and effective stimulation, an impedance analyzer is prov ...
Neuroprostheses were developed for a variety of applications using unique microfabrication methods. A technology platform that enables novel microelectrode array designs and microfluidic channels is described. Experiments demonstrating the in vivo utility ...
This paper presents the hardware realization and modeling of high-density microelectrode arrays including both microelectronic readout amplifiers as well as three-dimensional microelectrodes forming a fully integrated CMOS compatible system enabling resear ...
Microelectrode arrays (MEAs) are employed to study extracellular electrical activity in neuronal tissues. Neverthe- less, commercially available MEAs provide a limited number of recording sites and do not allow a precise identifi- cation of the spatio-temp ...
