Optimizing local capture of atrial fibrillation: a model based study of the influence of tissue dynamics on the outcome of rapid pacing
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Introduction: Rapid pacing of atrial fibrillation (AF) can induce local capture of the atrial tissue and preliminary studies showed that the septum area was the only location allowing capture of both atria from a single site. The present model-based study ...
In the present model-based study, the correlation dimension (D2) was used as a measure of the effectiveness of atrial septal pacing during atrial fibrillation (AF). From ongoing simulated atrial fibrillation, instantaneous transmembrane potential maps were ...
2014
Atrial fibrillation (AF) is the most common encountered cardiac rhythm disorder (arrhythmia) in clinical practice. It is responsible for about one third of arrhythmia-related hospitalizations. This arrhythmia, which increases in prevalence with age, leads ...
EPFL2014
We present a model-based study of therapeutical approaches to atrial fibrillation with a focus on pacing. After a systematic evaluation of different atrial pacing sites, we selected pacing from the septum area and designed a novel septum pacing protocol fo ...
Introduction: Electrical heterogeneity in the atria has been consistently linked with the initiation and perpetuation of atrial fibrillation (AF). The present model-based study investigated the contribution of action potential duration (APD) heterogeneitie ...
Introduction: Electrical heterogeneity in the atria has been consistently linked with the initiation and perpetuation of atrial fibrillation (AF). The present model-based study investigated the contribution of action potential duration (APD) heterogeneitie ...
Repolarization Alternans and Atrial Remodeling Introduction Paroxysmal atrial fibrillation (AF) may be triggered by intermittent atrial tachycardia, and ultimately lead to persistent AF. However, the mechanisms by which intermittent atrial tachycardia prom ...
Computer model-based simulations have shown that rapid stimulation at 60-100% of atrial fibrillation cycle length (AFCL) from a ring of electrodes located around the septum may induce local capture in both atria for most AF dynamics. The present study aims ...
2017
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The termination of long-standing persistent atrial fibrillation (LS-pAF) can be achieved by stepwise catheter ablation (step-CA) within the left atrium (LA). Our study aims to applying complexity measures derived from nonlinear time series analysis in orde ...
Objectives: Rapid pacing of atrial fibrillation (AF) can induce local atrial capture. The present model-based study investigated the impact of atrial tissue conduction velocity on AF capture ability during rapid septal pacing. Methods: The AF model combine ...