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Aligning data distributions that underwent spectral distortions related to acquisition conditions is a key issue to improve the performance of classifiers applied to multi-temporal and multi-angular images. In this paper, we propose a feature extraction me ...
Two short syntheses of D-N-Boc-3,5-bis(isopropyloxy)-4-methoxyphenylglycine, a central unit of vancomycin type antibiotics, have been developed. A diastereoselective Strecker amination reaction using (S)-phenylglycinol as a chiral inducer was the key step ...
A convergent total synthesis of sanjoinine G1 (I), a 14-membered cyclopeptide alkaloid was described. Formation of aryl alkyl ether bond with concomitant construction of macrocycle by way of an intramol. SNAr reaction was the key step in this synthesis. On ...
A system for off-line cursive script recognition is presented. A new normalization technique (based on statistical methods) to compensate for the variability of writing style is described. The key problem of segmentation is avoided by applying a sliding wi ...
A system for off-line cursive script recognition is presented. A new normalization technique (based on statistical methods) to compensate for the variability of writing style is described. The key problem of segmentation is avoided by applying a sliding wi ...
the strategy involving the use of functionalized tetrahydro-6H-cycloocta[b]indol-6-one is reported as a key intermediate for synthesis of members of the sarpagine-ajmaline-macroline family of monoterpene indole alkaloids. The desired tricycle was synthesiz ...
Amatoxins are ribosomally synthesized and post-translationally modified bicyclic octapeptides biosynthesized by the deadly basidiomycete fungus Amanita phalloides. Amongst this group, alpha-amanitin is the most widely known toxin and is currently under inv ...
The development of efficient routes to multi gram quantities of chiral synthons is a key issue in total synthesis of natural products and analogues. The conformationally defined and rigid 8-oxabicyclo[3.2.1]oct-6-en-3-one template appears as an appealing s ...
Total syntheses of (±)-goniomitine, (±)-1,2-dehydroaspidospermidine, (±)-aspidospermidine, (±)-vincadifformine, and (±)-kopsihainanine A were achieved featuring two common key steps: (1) a palladium-catalyzed decarboxylative vinylation that provides quick ...
A synthesis of L,L-N,N-dimethylcycloisodityrosine (I) based on an intramol. SNAr reaction is reported. A possible explanation was proposed to account for the facile epimerization encountered in the cycloetherification of dipeptide L,L-II and a soln. to thi ...
