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MR is a well-established technique routinely used in preclinical and clinical studies. This thesis focussed on the improvement of sensitivity of different methods in MR.Hyperpolarized 129Xe gas is used for studying pulmonary disease or cerebral perfusion ...
The modeling of the diffusion MRI signal from moving and deforming organs such as the heart is challenging due to significant motion and deformation of the imaged medium during the signal acquisition. Recently, a mathematical formulation of the Bloch-Torre ...
Magnetic resonance resonance (MRI) is a widely used modality to obtain in vivo tissue information.
Clinical applications are near countless, and almost all body parts can be examined using an MR
scanner. As the method is non invasive, does not use ionizing ...
The modeling of the diffusion MRI signal from moving and deforming organs such as the heart is challenging due to significant motion and deformation of the imaged medium during the signal acquisition. Recently, a mathematical formulation of the Bloch-Torre ...
Functional magnetic resonance imaging is a galvanizing tool for behavioral scientists. It provides a means by which to see what the brain does while a person thinks, acts, or perceives, without invasive procedures. In this, fMRI affords us a relatively eas ...
Magnetic Resonance Imaging combined with hyperpolarized C-13-labelled metabolic contrast agents produced via dissolution Dynamic Nuclear Polarization can, non-invasively and in real-time, report on tissue specific aberrant metabolism. However, hyperpolariz ...
Purpose To obtain whole-brain high-resolution T-2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. Methods A ...
Purpose To develop a 3D MR technique to simultaneously acquire proton multiparametric maps (T-1, T-2, and proton density) and sodium density weighted images over the whole brain. Methods We implemented a 3D stack-of-stars MR pulse sequence which consists o ...
Magnetic resonance imaging is widely used in medical diagnosis to obtain anatomical details of the human body in a non-invasive way. Clinical MR scanners typically operate at a static magnetic field strength (B0) of 1.5T or 3T. However, going to higher fie ...
The impact of in-scanner motion on functional magnetic resonance imaging (fMRI) data has a notorious reputation in the neuroimaging community. State-of-the-art guidelines advise to scrub out excessively corrupted frames as assessed by a composite framewise ...