Arterial remodeling in response to increased blood flow using a constituent-based model
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This thesis aims at better understanding the role played by vascular smooth muscle cells (VSM) in the biomechanics of the arterial wall. Current models assume that under maximal vasodilation VSM carry no load, or the so-called "active stress" is zero. Biom ...
Arterial spin labeling (ASL) is a method of using MRI to image cerebral perfusion. For the measurement to be calibrated, a model is required describing the kinetics of the flow of the inverted blood from the labeling region to the imaging region. It is com ...
The main objective was to evaluate a Scanning Laser Ophthalmoscope (SLO) based particle tracking method as a means of quantitative assessment of retinal blood velocity and vessel diameter changes in response to hypoxia and hyperoxia. Retinal blood velociti ...
Hypertension-induced arterial remodeling has been previously modeled using stress-driven remodeling rate equations in terms of global geometrical adaptation (Rachev A, Stergiopulos N, Meister JJ. Theoretical study of dynamics of arterial wall remodeling in ...
Vascular remodeling is defined as any enduring change in the size and composition of an adult blood vessel, allowing adaptation or repair. The vascular remodeling response has been shown to depend on a variety of endogenous and environmental factors. Physi ...
Acute and long-term (up to 56 days) evolution of geometry, structural properties, vascular smooth muscle (VSM) tone and histomorphometric properties of the rat common carotid arteries under induced hypertension were investigated. Hypertension was induced i ...
Hemodynamics have crucial role in the control of vascular tone, in the regulation of arterial remodeling, and in the production of mediators that maintain arterial function. Changes in hemodynamics forces induce profound alterations in vascular cell metabo ...
In this note, we propose Steklov-Poincaré iterative algorithms (mutuated from the analogy with heterogeneous domain decomposition) to solve fluidstructure interaction problems. Although our framework is very general, the driving application is concerned wi ...
The aim of this work is to provide mathematically sound and computationally effective tools for the numerical simulation of the interaction between fluid and structures as occurring, for instance, in the simulation of the human cardiovascular system. This ...
ACE inhibitory peptides are biologically active peptides that play a role in blood pressure regulation. When derived from food proteins during food processing or gastrointestinal digestion, these peptides could function as efficient agents in treating and ...