Theoretical study of dynamics of arterial wall remodeling in response to changes in blood pressure
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This thesis is intended to contribute to the field of biomechanics of growth and remodeling of arteries. The work focuses particularly on growth and remodeling caused by sustained hypertension, increased blood flow, and ageing. A structure-based constituti ...
A new model considering fixed and interlocked cracks for the analysis of reinforced concrete (RC) cracked membrane elements is presented. The model can be regarded as an extension of the cracked membrane model proposed by Kaufmann and Marti. Its value lies ...
Due to the pulsatile nature of blood flow, arteries are constantly exposed to dynamic mechanical forces; the pulsatility continuously stretches the vessel wall and the flow creates a frictional force on the interior surface. These stresses, referred to as ...
Reymond P, Bohraus Y, Perren F, Lazeyras F, Stergiopulos N. Validation of a patient-specific one-dimensional model of the systemic arterial tree. Am J Physiol Heart Circ Physiol 301: H1173-H1182, 2011. First published May 27, 2011; doi:10.1152/ajpheart.008 ...
A distributed model of the human arterial tree including all main systemic arteries coupled to a heart model is developed. The one-dimensional (1-D) form of the momentum and continuity equations is solved numerically to obtain pressures and flows throughou ...
Previous theoretical models of arterial remodeling in response to changes in blood flow were based on the assumption that material properties of the arterial wall remain unchanged during the remodeling process. According to experimental findings, however, ...
The determination of the thermal and athermal stress components using relaxation experiments along a stress-strain curve is critically evaluated. Short-term stress-relaxations are performed along the stress-strain curve of single crystals of Ge at 850 K, C ...
This thesis aims at better understanding the role played by vascular smooth muscle cells (VSM) in the biomechanics of the arterial wall. Current models assume that under maximal vasodilation VSM carry no load, or the so-called "active stress" is zero. Biom ...
The creep of a dislocation on its glide plane is essentially controlled by three different stress fields: the external applied stress, the internal stress field due to a multi-scale hierarchy of different obstacles (the structural defects acting on the dis ...
Earlier experimental work on decellularized arteries revealed the existence of significant residual stresses within the arterial wall, which are released upon chemical removal of vascular smooth muscle in normal arteries causing substantial radial expansio ...