Publication

Three-Dimensional Magnetic Focusing of Superparamagnetic Beads for On-Chip Agglutination Assays

Publications associées (36)

Microfluidic devices

The present disclosure relates to a microfluidic device comprising: a substrate; a culture chamber (130); a loading channel (170) in fluid communication with the culture chamber; at least one auxiliar channel (170-1, 5 170-2) extending from and in fluid co ...

2023

Efficient AC electrothermal flow (ACET) on-chip for enhanced immunoassays

Martinus Gijs, Diego Gabriel Dupouy, Muaz Salama Abdelmonem Draz

Biochemical reaction rates in microfluidic systems are known to be limited by the diffusional transport of reagents, leading often to lowered sensitivity and/or longer detection times in immunoassays. Several methods, including electrically powering electr ...

ROYAL SOC CHEMISTRY2023

Development of next-generation microfluidic systems for enhanced, faster, and cost-effective immunoassays for tissue diagnostics - Ac electrothermal flow & Acoustofluidics

Muaz Salama Abdelmonem Draz

The application of microfluidics in the field of surface-based assays and more specifically, the spatial molecular profiling of tumor tissues has gained a lot of interest, especially with the increased interest in personalized medicine and targeted therapy ...

EPFL2023

Rapid Characterization and Quantification of Extracellular Vesicles by Fluorescence-Based Microfluidic Diffusion Sizing

Pablo Rivera Fuentes, Adam Miklos Eördögh

Extracellular vesicles (EVs) are emerging as promising diagnostic and therapeutic tools for a variety of diseases. The characterization of EVs requires a series of orthogonal techniques that are overall time- and material-consuming. Here, a microfluidic de ...

WILEY2021

Linear triglycerol-based fluorosurfactants show high potential for droplet-microfluidics-based biochemical assays

Esther Amstad, Irvine Lian Hao Ong, Abhishek Kumar Singh

Fluorosurfactants have expanded the landscape of high-value biochemical assays in microfluidic droplets, but little is known about how the spatial geometries and polarity of the head group contribute to the performance of fluorosurfactants. To decouple thi ...

ROYAL SOC CHEMISTRY2021

Microfluidic devices for the study of cell-cell, cell-particle and particle-particle interactions

Margaux Catherine Marie Duchamp

Microfluidics and microtechnologies are of great interest for biological applications. This interest is linked to the fact that microtechnologies enable the study of single cells at the cellular and sub-cellular level. One of many applications of such sing ...

EPFL2020

Pattern formation in thin liquid films: from coating-flow instabilities to microfluidic droplets

Gioele Mariano Nicolò Balestra

Nature and technical applications abound with thin viscous flows, ranging from the lava flow on volcanoes to the lubricating layer around confined bubbles in the microchannels of Lab-on-a-Chip devices. Countless are the examples where coating flows arise i ...

EPFL2018

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The Caenorhabditis elegans embryo is a widely used model for the functional analysis of dynamic cellular processes, such as chromosome segregation, cytokinesis or lineage analysis. However, the conventional embryo preparation method that relies on manually ...

Ieee2017

Microfluidic-integrated vertical electrodes employed in impedance-based cytometry

Enrica Rollo

During the last decades, the growing interest for single-cell analysis has led to the creation of a number of microfluidic and lab-on-a chip (LOC) platforms for characterizing cellular samples. In that context label-free based platforms are minimally invas ...

EPFL2016

High-throughput nanoimmunoassay chip

Sebastian Maerkl, Jose Luis Garcia Cordero

The nanoimmunoassay chip comprises at least flow and control layers, divided into several rows, each row containing a plurality of single assay units, each assay unit contains two spotting chambers (1) and an assay chamber in the middle, wherein neck valve ...

2015

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