In-vivo measurement of fluorescence bleaching of meso-tetra hydroxy phenyl chlorin (mTHPC) in the esophagus and the oral cavity
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A non-invasive probe has been devised and clinically used to perform in vivo measurements of the optical properties of the esophageal wall and oral cavity. The absorption and reduced scattering coefficients are determined from the observation of the spatia ...
BACKGROUND AND OBJECTIVE: Under standardized conditions (drug and light dose, timing), the result of the photodynamic therapy (PDT) of carcinomas of the esophagus with tetra(meta-hydroxyphenyl)chlorin (mTHPC) shows large variations between patients. STUDY ...
The paper presents a qualitative analysis of an array of diffusively coupled identical continuous time dynamical systems.The effects of full, partial, anti-phase and in-phase-anti-phase chaotic synchronization are investigated via the linear invariant mani ...
The pharmacokinetics (PK) of the photosensitizer tetra(m-hydroxyphenyl)chlorin (mTHPC) was measured by optical fiber-based light-induced fluorescence spectroscopy (LIFS) in the normal and tumoral cheek pouch mucosa of 29 Golden Syrian hamsters with chem. i ...
A new way of teaching differential equations with interdisciplinary models and a computer is presented. The models are taken from physics, chemistry and biology. Students work at the computer in interactive use. They have the choice of the values of differ ...
The pharmacokinetics of the photosensitizer 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (mTHPC) was investigated in the plasma of 20 patients by absorption and fluorescence spectroscopy. The temporal behavior was characterized by a rapid decrease in concn. du ...
In vivo spectrofluorometric analysis during photodynamic therapy (PDT) is a tool to obtain information about fluorophore bleaching kinetics in tissue. Using a cylindrical esophageal light distributor for PDT with an integrated sensing fiber, together with ...
This work investigates the trajectory method [1] for the reconstruction of ordinary differential equations (ODEs) from time series. The potentials of the method are analyzed for dynamical systems described by second- and third-order ODEs, focusing in parti ...
