Physiological adaptation of Desulfitobacterium hafniense strain TCE1 to tetrachloroethene respiration
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Tuberculosis is an ancient human disease affecting millions of people every year. The common causative agent, Mycobacterium tuberculosis, is a peculiar pathogen that can persist in the host tissues for decades. Many of the key attributes of M. tuberculosis ...
Sulfurospirillum multivorans is an epsilonproteobacterium able to grow anaerobically with hydrogen as electron donor and tetrachloroethene (PCE) as terminal electron acceptor (organohalide respiration). The dechlorination is mediated by the PCE reductive d ...
The brain has very high energy demands that are mainly met by the circulating blood glucose to ensure its proper functioning. Thus, it is not surprising that though the human brain weighs only 2- 3% of the body weight, it consumes approximately 25% of tota ...
Tryptophan is commonly used to study protein structure and dynamics, such as protein folding, as a donor in fluorescence resonant energy transfer (FRET) studies. By using ultra-broadband ultrafast two-dimensional (2D) spectroscopy in the ultraviolet (UV) a ...
American Association for the Advancement of Science2013
Desulfotomaculum reducens is the first Gram-positive sulfate- and metal-reducing bacterium for which the transcriptomic response to uranium exposure has been evaluated. The genes upregulated during fermentative growth in the presence of U(VI) as compared t ...
Genome-scale metabolic reconstructions (GSMRs) are valuable resources in the analysis and understanding of cellular metabolism. They are based on genome sequence and annotation, and they are to develop bottom-up mathematical models of metabolic networks. T ...
The specific labeling of proteins with synthetic probes is a powerful approach to study protein function and protein tags have been widely used for this purpose. A well-established example for a self-labeling protein tag is SNAP-tag. It specifically reacts ...
Remarkable advances have been made during the last few decades in defining the organizational principles of the secretory pathway. The Golgi complex in particular has attracted special attention due to its central position in the pathway, as well as for it ...
Organohalide respiration (OHR) is a bacterial anaerobic energy metabolism that uses many chlorinated organic compounds as terminal electron donors. The process is catalyzed by a class of complex redox enzymes called reductive dehalogenases which harbour a ...
The bioenergetics efficiency of aerobic respiration of an organism is expressed through P/O ratio, which represents the ATP production per oxygen atom reduced in Electron Transport Chains (ETC). P/O ratio, to date, has not been extensively used in the cont ...
