Publication
Coat color dilution in mice because of inactivation of the melanoma antigen MART-1
Publications associées (53)
The mouse tyrosinase promoter is sufficient for expression in melanocytes and in the pigmented epithelium of the retina
The mouse c locus encodes tyrosinase (monophenol monooxygenase; monophenol, L-dopa:oxygen oxidoreductase, EC 1.14.18.1), the key enzyme in melanin synthesis, which is expressed in the pigment epithelium of the retina and in melanocytes derived from the neu ...
1991Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice
The c-locus of the mouse is thought to encode tyrosinase, the key enzyme for melanin synthesis in melanocytes of the skin and the eye. Recently, a mouse cDNA was isolated and shown to confer tyrosine activity on a cell line which expressed no specialized f ...
1990Suppression of melanoma development and regression of melanoma in xiphophorine fish after treatment with immune RNA
In xiphophorine fish suffering from a genetically caused melanoma, both suppression of melanoma development and regression of the existing melanoma were observed after treatment of the fish with an "anti-melanoma immune RNA." This RNA was extracted from th ...
1981