Pyridine-Based Lanthanide Complexes Combining MRI and NIR Luminescence Activities
Graph Chatbot
Chattez avec Graph Search
Posez n’importe quelle question sur les cours, conférences, exercices, recherches, actualités, etc. de l’EPFL ou essayez les exemples de questions ci-dessous.
AVERTISSEMENT : Le chatbot Graph n'est pas programmé pour fournir des réponses explicites ou catégoriques à vos questions. Il transforme plutôt vos questions en demandes API qui sont distribuées aux différents services informatiques officiellement administrés par l'EPFL. Son but est uniquement de collecter et de recommander des références pertinentes à des contenus que vous pouvez explorer pour vous aider à répondre à vos questions.
Gadolinium‐loaded nanomicelles show promise as future magnetic resonance imaging (MRI) contrast agents (CAs). Their increased size and high gadolinium (Gd) loading gives them an edge in proton relaxivity over smaller molecular Gd‐complexes. Their size and ...
Here we report the straightforward synthesis of the ligands L-tz, L-tzC8, L-tzPEG, L-tzAnis and L-=Anis presenting the same pyridine-bistetrazolate (pytz, L) chelating scaffold but different substituents on the para position of the pyridine ring. Its subst ...
Three PEGylated derivatives of 6-amino-2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]hexanoic acid (DOTA-AHA) with different molecular weights were prepared and characterized. Their Gd-III chelates were studied in aqueous solution through v ...
Complexes of lanthanide (III) ions have been used in structural studies of biomolecules and as contrast agents (CA). Clinically approved CAs have only one water molecule in their first coordination sphere. Structure and water exchange rate of these complex ...
The displacement of water molecule(s) from the inner coordination sphere of [Gd(DTTA–Me)(H2O)2]− (DTTA = ethylenetriamine-N,N,N″,N″-tetraacetate) by fluoride has been studied by multinuclear NMR relaxation (1H, 17O, 19F) and DFT calculations. Fluoride anio ...
This essay draws attention to lanthanide luminescence by putting into perspective the sensitization process of f-f emission, the design of highly luminescent lanthanide-based compounds, and upconversion nanoparticles. A brief overview of the recent advance ...
The need for magnetic resonance imaging (MRI) contrast agents with improved relaxivity maintains the development of new Gd-III chelates as an intensive and demanding field of research. In this work, we introduce the new dimeric chelators bis{1,4,7,10-tetra ...
Magnetic resonance imaging is one of the most efficient diagnostic modalities in clinical radiology and biomedical research. To enhance image contrast, paramagnetic complexes, mainly Gd3+ chelates, are used. Today, around one third of all medical MR images ...
Water exchange kinetics of [Ln(L)(H2O)2]x complexes (Ln = Pr, Nd, Dy, Tm, and Yb; L = DO3A and DTTA–Me) were studied by 17O NMR spectroscopy as a function of temperature, pressure, and frequency and by 1H nuclear magnetic relaxation dispersion. Water excha ...
Homoleptic acetonitrile complexes [Nd(CH3CN)(9)]Al(OC(CF3)(3))(4), [Dy(CH3CN)(9)]Al(OC(CF3)(3))(4), and [Tm(CH3CN)(8)]Al(OC(CF3)(3))(4) have been studied in anhydrous acetonitrile by 14N and 1H NMR relaxation. Solvent-exchange rate constants ...
