Publication
Systolic Hypertension Mechanisms: Effect of Global and Local Proximal Aorta Stiffening on Pulse Pressure
Publications associées (73)
The effect of the elongation of the proximal aorta on the estimation of the aortic wall distensibility
Nikolaos Stergiopoulos, Georgios Rovas, Bram Trachet, Vasiliki Bikia, Stamatia Zoi Pagoulatou, Mauro Ferraro
The compliance of the proximal aortic wall is a major determinant of cardiac afterload. Aortic compliance is often estimated based on cross-sectional area changes over the pulse pressure, under the assumption of a negligible longitudinal stretch during the ...
2020System for closed loop control of autonomic function
Grégoire Courtine, Jordan Squair
A neuromodulation system (10,110) is disclosed, especially a neurostimulation system (10,110), for treating a patient, especially for enhancing at least one autonomous function such a blood circulation and/or respiration, wherein the system comprises • - a ...
2020On the importance of the nonuniform aortic stiffening in the hemodynamics of physiological aging
Nikolaos Stergiopoulos, Bram Trachet, Vasiliki Bikia, Stamatia Zoi Pagoulatou
Mathematical models of the arterial tree constitute a valuable tool to investigate the hemodynamics of aging and pathology. Rendering such models as patient specific could allow for the assessment of central hemodynamic variables of clinical interest. Howe ...
AMER PHYSIOLOGICAL SOC2019Estimating Left Ventricular Elastance from Aortic Flow Waveform, Ventricular Ejection Fraction, and Brachial Pressure: An In Silico Study
Nikolaos Stergiopoulos, Stamatia Zoi Pagoulatou
Although left ventricular end-systolic elastance (E-es) serves as a major index of cardiac contractility, a widely-accepted noninvasive estimation of E-es does not exist. To overcome this limitation, we developed a two-step inverse method that allows for i ...
SPRINGER2018Total arterial compliance, estimated by a novel method, is better related to left ventricular mass compared to aortic pulse wave velocity: The SAFAR study
Aim: The investigation of the association between total arterial compliance (C-T)-estimated by a novel technique-with left ventricular mass (LVM) and hypertrophy (LVH). Our hypothesis was that C-T may be better related to LVM compared to the gold-standard ...
Taylor & Francis Inc2017Effect of Exercise on Baroreflex at Different Altitudes
Jean-Marc Vesin, Sasan Yazdani
Various studies have been performed to analyze and asses the baroreflex sensitivity (BRS) in different settings. Our study aims at analyzing the BRS at rest and during different exercise stages and altitudes. Twenty-one young, healthy subjects underwent ex ...
2016Accuracy of commercial devices and methods for noninvasive estimation of aortic systolic blood pressure a systematic review and meta-analysis of invasive validation studies
Nikolaos Stergiopoulos, Thomas Alois Weber
Background: Although compelling evidence has established the physiological and clinical relevance of aortic SBP (a-SBP), no consensus exists regarding the validity of the available methods/techniques that noninvasively measure it. Objectives: The systemati ...
Lippincott, Williams & Wilkins2016Novel non-invasive techniques for hemodynamic monitoring
The monitoring of hemodynamic parameters is crucial for optimal patient management and treatment. However, established methods are often invasive and possibly inapplicable to sensitive age groups. Novel, non-invasive techniques have the potential to transf ...
EPFL2014First in vivo application and evaluation of a novel method for non-invasive estimation of cardiac output
Nikolaos Stergiopoulos, Orestis Vardoulis
Surgical or critically ill patients often require continuous assessment of cardiac output (CO) for diagnostic purposes or for guiding therapeutic interventions. A new method of non-invasive CO estimation has been recently developed, which is based on press ...
Elsevier2014Effects of Isoflurane Anesthesia on Aortic Compliance and Systemic Hemodynamics in Compliant and Noncompliant Aortas
Objectives: To investigate the effect of general anesthesia on aortic compliance and other cardiovascular hemodynamics in chronically instrumented pigs with compliant and noncompliant (stiff) aortas. Design: Experimental study. Setting: University animal l ...
W B Saunders Co-Elsevier Inc2013