An Efficient One-Step Synthesis of Piperidin-2-yl and Pyrrolidin-2-yl Flavonoid Alkaloids through Phenolic Mannich Reactions
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The asymmetric synthesis of long chain di- and tri-amino polyols is reported. The developed methodology is based on the functionalization of 3,3'-methylenebis{[6-(benzyloxy)methoxy]cyclohept-3-en-1-ol} derivatives that allows the selective introduction of ...
