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Functional and structural connectivity alterations in short- and long-range projections have been reported across neurodevelopmental disorders (NDD). Interhemispheric callosal projection neurons (CPN) represent one of the major long-range projections in th ...
In the past 20 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...
2023
The present thesis aimed at investigating behavioral and neural underpinnings of the mechanisms related to the different aspects of self-monitoring. The first aim was to study functional connectivity alterations related to the mechanisms accounting for the ...
EPFL2020
In visual backward masking (VBM), a target is followed by a mask. Over the past decade, a VBM task, called the Shine-Through paradigm (ST), has been shown to be a very sensitive endophenotype of schizophrenia. In the present thesis, the electrophysiologica ...
EPFL2019
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Objective: In visual backward masking, a target is followed by a mask, which deteriorates performance on the target. Masking is a very sensitive endophenotype for schizophrenia. Patients and their siblings (to a lesser extent) show strong performance defic ...
2019
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Introduction: Electroencephalogram (EEG) microstates are on-going scalp potential configurations that remain stable for around 80 ms (1). Four recurrent and dominant classes of microstates (labeled A-D) are observed in resting-state EEG, explaining around ...
2019
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Objective: Electroencephalogram (EEG) microstates are on-going scalp potential configurations that remain stable for around 80 ms. Abnormal temporal dynamics of specific classes of microstates have been suggested as a potential endophenotype for schizophre ...
2019
Investigating potential gray matter differences in adolescents presenting higher levels of schizotypy personality traits could bring further insights into the development of schizophrenia spectrum disorders. Research has yet to examine the morphological co ...
2020
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Objective: Schizophrenia is a heterogeneous disease strongly influenced by genetic disposition. However, genetic studies have shown that each single nucleotide polymorphism (SNP) contributes very little to the disease. For this reason, endophenotypes, loca ...
Exposure to childhood trauma (CT) increases the risk for psychosis and affects the development of brain structures, possibly through oxidative stress. As oxidative stress is also linked to psychosis, it may interact with CT, leading to a more severe clinic ...
