European phylogeography of the epiphytic lichen fungus Lobaria pulmonaria and its green algal symbiont
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Beneficial mutations can co-occur when population structure slows down adaptation. Here, we consider the process of adaptation in asexual populations distributed over several locations ("islands"). New beneficial mutations arise at constant rate u(b), and ...
As the focus of human genetics shifts from Mendelian traits to complex diseases, a sophisticated genetic tool kit—with space for genetics (classical, molecular, statistical, and quantitative), metabolics, proteomics, bioinformatics, and mathematics—is requ ...
With the advent of next-generation sequencing technologies, large data sets of several thousand loci from multiple conspecific individuals are available. Such data sets should make it possible to obtain accurate estimates of population genetic parameters, ...
A workshop recently held at the École Polytechnique Fédérale de Lausanne (EPFL, Switzerland) was dedicated to understanding the genetic basis of adaptive change, taking stock of the different approaches developed in theoretical population genetics and land ...
The NextGen project investigates disease resistance in indigenous Ugandan cattle. Since population structure and stratification may produce biased results, We have investigated the genomic structure of sampled animals genotyped with the BovineSNP50 Genotyp ...
The domestic goat is one of the five most important livestock species worldwide and plays an important role in the livelihood of a large proportion of small and marginal farmers and landless shepherds. To serve as a rational basis for the conservation of g ...
Extinction, recolonization and local adaption are common in natural spatially structured populations. Understanding their effect upon genetic variation is important for systems such as GMO management, or avoidance of drug resistance. Theoretical studies on ...
The maintenance of sexual reproduction remains one of the major puzzles of evolutionary biology, since, all else being equal, an asexual mutant should have a twofold fitness advantage over the sexual wildtype. Most theories suggest that sex helps either to ...
Genetic diversity is essential for population survival and adaptation to changing environments. Demographic processes (e.g., bottleneck and expansion) and spatial structure (e.g., migration, number, and size of populations) are known to shape the patterns ...
In 2007, FAO (Food and Agriculture Organization, from the United Nations) initiated the Global plan of action for Farm Animal Genetic Resources (FAnGR) to reduce further loss of genetic diversity in farm animals. One of the key issues mentioned is to ident ...
