Atrial septal pacing for the termination of atrial fibrillation: study in a biophysical model of human atria
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Atrial fibrillation (AF) is the most common arrhythmia observed in clinical practice. It is responsible for about one third of hospitalizations related to problems of arrhythmia. AF is an important clinical entity due to the increased risk of morbidity and ...
Stepwise catheter ablation (step-CA) can terminate long-standing persistent atrial fibrillation (LS-pAF) within the left atrium (LA) or may require additional right atrial (RA) ablation. Intracardiac organization indices such as AF cycle length (AFCL) have ...
Rapid pacing of atrial fibrillation (AF) can induce local capture of the atrial tissue. Heterogeneities in atrial substrate are considered to play in the perpetuation of AF by promoting AF reentries. The present model-based study investigated the influence ...
Introduction: Rapid pacing of atrial fibrillation (AF) can induce local capture of the atrial tissue and preliminary studies showed that the septum area was the only location allowing capture of both atria from a single site. The present model-based study ...
Introduction: We recently observed in human left atrium periods of intermittent 2:1 and 1:1 atrial capture, preceded by atrial repolarization alternans (Re-ALT) during rapid pacing. It remains undetermined whether Re- ALT plays a role in preventing 1:1 atr ...
The aim of this work is to present different markers resulting from the analysis of a single ECG lead recorded during sinus rhythm. To this purpose, the ECGs from three populations were compared: healthy subjects, patients subject to paroxysmal AF selected ...
Interdisciplinary collaboration between physicians and engineers is now widespread in fundamental and clinical studies, due to the increasing complexity of the physiological problems tackled, and the development of novel measurement devices and data analys ...
Purpose: Experimental studies showed that local capture of atrial fibrillation (AF) by rapid pacing was possible in humans. However, contradictory observations were reported on its effect at distant atrial sites. The present model-based study investigated ...
Introduction: We recently observed in an acute ovine model of pacing-induced atrial tachycardia (PIAT) that rapid atrial capture and fibrillatory conduction were prevented by 2:1 capture mediated by decreased excitability. We hypothesize that long-term int ...
Atrial fibrillation is the most common cardiac rhythm disorder encountered in clinical practice, often leading to severe complications such as heart failure and stroke. This arrhythmia, increasing in prevalence with age, already affects several millions of ...