Organometallic anticancer agents that interfere with cellular energy processes: a subtle approach to inducing cancer cell death

Paul Joseph Dyson, Rosario Scopelliti, Alexey Nazarov, Mathurin Baquié, Daniel Gardini
2013
Article

Résumé

Two hybrid compounds comprising an antimetastatic rutheniumarene fragment tethered to an indazole-3-carboxylic acid derivative that inhibits aerobic glycolysis in cancer cells have been prepared and evaluated in a variety of cancer cell lines, including highly relevant human glioblastoma cells, with an apparent synergistic action between the two components observed.

Source officielle

https://infoscience.epfl.ch/record/185208?ln=fr

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