Publication
Microfluidics for in vitro biomimetic shear stress-dependent leukocyte adhesion assays
Publications associées (38)
Fault roughness’s influence on experimental fault mechanical behavior
Brice Tanguy Alphonse Lecampion, Marie Estelle Solange Violay, Barnaby Padraig Fryer, Seyyedmaalek Momeni, François Xavier Thibault Passelègue, Carolina Giorgetti
Fault slip behavior and earthquake nucleation are often framed within the context of velocity-dependent friction, ranging from velocity-strengthening to velocity-weakening behavior. Previous studies have shown that fault roughness controls the fault slip b ...
2022Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist
Henning Paul-Julius Stahlberg, Nicolas Calo, Polina Isaikina
The human CC chemokine receptor 5 (CCR5) is a G protein-coupled receptor (GPCR) that plays a major role in inflammation and is involved in cancer, HIV, and COVID-19. Despite its importance as a drug target, the molecular activation mechanism of CCR5, i.e., ...
AMER ASSOC ADVANCEMENT SCIENCE2021Analysis of morphological and hemodynamical indexes in abdominal aortic aneurysms as preliminary indicators of intraluminal thrombus deposition
Alfio Quarteroni, Simone Deparis, Claudia Maria Colciago
In this paper, we study the correlation between the wall shear stress, a hemodynamical index derived from numerical simulations, and an new index MFA-ILT for the characterization of intraluminal thrombus (ILT) in the presence of abdominal aortic aneurysms. ...
2020Hydraulic Transport Through Calcite Bearing Faults With Customized Roughness: Effects of Normal and Shear Loading
Marie Estelle Solange Violay, Mateo Alejandro Acosta
Understanding fluid flow in rough fractures is of high importance to large scale geologic processes and to most anthropogenic geo‐energy activities. Here we conducted fluid transport experiments on Carrara marble fractures with a novel customized surface t ...
2020Analysis of morphological and haemodynamical indexes in abdominal aortic aneurysms as preliminary indicators of intraluminal thrombus deposition
Alfio Quarteroni, Simone Deparis, Claudia Maria Colciago
In this paper we study the correlation between the Wall Shear Stress (WSS), a haemodynamical index derived from numerical simulations, and an new index MFA-ILT for the characterisation of intraluminal thrombus (ILT) in presence of abdominal aortic aneurysm ...
2019A model for cellular mechanotransduction and contractility at finite strain
William Curtin, Mahmut Selman Sakar, Nikolaos Bouklas
In this work we introduce a theoretical and computational modeling framework for the contractile response of single cells triggered by external mechanical stimuli. The structural response due to the formation and dissociation of stress fibers is modeled fo ...
2018A model for cellular mechanotransduction and contractility at finite strain
William Curtin, Mahmut Selman Sakar, Nikolaos Bouklas
In this work we introduce a theoretical and computational modeling framework for the contractile response of single cells triggered by external mechanical stimuli. The structural response due to the formation and dissociation of stress fibers is modeled fo ...
2018FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature
Nadine Fournier, Mauro Delorenzi, Yan Agalarov, Esther Bovay
Biomechanical forces, such as fluid shear stress, govern multiple aspects of endothelial cell biology. In blood vessels, disturbed flow is associated with vascular diseases, such as atherosclerosis, and promotes endothelial cell proliferation and apoptosis ...
American Society for Clinical Investigation2015Porous thick-film silver metallisation for thermally mismatched brazing operations in tokamak magnetic sensor
Duccio Testa, Peter Ryser, Lucas Güniat, Thomas Maeder, Caroline Jacq, Adrien Aymeric Thibault Corne
A novel sensor based on thick-film + LTCC (low-temperature cofired ceramic) technology has been recently developed for sensing high-frequency 3D magnetic fields in tokamak fusion devices. For integration within the walls of the tokamak, the sensor has to b ...
IMAPS / ACerS2015Fundamental Constraints on the Abundances of Chemotaxis Proteins
Anne-Florence Raphaëlle Bitbol
Flagellated bacteria, such as Escherichia coli, perform directed motion in gradients of concentration of attractants and repellents in a process called chemotaxis. The E. coli chemotaxis signaling pathway is a model for signal transduction, but it has uniq ...
Elsevier BV2015