Publication

Microfluidic Droplet-Based Liquid–Liquid Extraction and On-Chip IR Spectroscopy Detection of Cocaine in Human Saliva

Publications associées (32)

Microfluidic devices

The present disclosure relates to a microfluidic device comprising: a substrate; a culture chamber (130); a loading channel (170) in fluid communication with the culture chamber; at least one auxiliar channel (170-1, 5 170-2) extending from and in fluid co ...

2023

Facile Fabrication of Microfluidic Chips for 3D Hydrodynamic Focusing and Wet Spinning of Polymeric Fibers

Fabien Sorin, René M. Rossi, Efe Armagan, Claudio Toncelli, Akin Gürsoy

Microfluidic wet spinning has gained increasing interest in recent years as an alternative to conventional wet spinning by offering higher control in fiber morphology and a gateway for the development of multi-material fibers. Conventionally, microfluidic ...

2020

Studying the roundworm Caenorhabditis elegans using microfluidic chips

Martinus Gijs

C. elegans is an attractive model organism in biology, as it shows genetic similarity with humans, facilitates microscopic observation due to its transparency, and has a short life cycle. Moreover, many mutants expressing fluorescent proteins in particular ...

SPIE-INT SOC OPTICAL ENGINEERING2019

Microfluidic-integrated vertical electrodes employed in impedance-based cytometry

Enrica Rollo

During the last decades, the growing interest for single-cell analysis has led to the creation of a number of microfluidic and lab-on-a chip (LOC) platforms for characterizing cellular samples. In that context label-free based platforms are minimally invas ...

EPFL2016

Heterogeneous Integration of Low Power pH FinFET sensors with Passive Capillary Microfluidics and miniaturized Ag/AgCl quasi-Reference Electrode

Mihai Adrian Ionescu, Erick Antonio Garcia Cordero, Hoël Maxime Guérin, Francesco Bellando, Amira Muhech Medrano

This work presents one of the first low power pH sensing microfluidic chip based on the heterogeneous integration of: (i) high-k FinFET sensors with liquid gate, (ii) miniaturized Ag/AgCl quasi-Reference Electrode and (iii) passive microfluidic. The integr ...

Ieee2016

Programming and use of Parylene C fluorescence as a quantitative on-chip reference

Martinus Gijs, Diego Gabriel Dupouy, Ata Tuna Ciftlik, Joan Teixidor

A large number of lab-on-a-chip applications use fluorescence for quantifying biological entities. In such applications, incorporation of a stable on-chip fluorescent reference source would be highly desirable in order to compensate for instrumental parame ...

Royal Soc Chemistry2014

Nanoscale spatially resolved infrared spectra from single microdroplets

Giovanni Dietler, Andrzej Kulik, Francesco Simone Ruggeri

Droplet microfluidics has emerged as a powerful platform allowing a large number of individual reactions to be carried out in spatially distinct microcompartments. Due to their small size, however, the spectroscopic characterisation of species encapsulated ...

Royal Society of Chemistry2014

Opportunities for high-pressure microfluidics in biomedical applications

Ata Tuna Ciftlik

Pressure lies at the basis of operation of most microfluidic systems, and is a determinant factor in the extent of miniaturization and in limiting the throughput and time constant of the microfluidic assays. Despite the apparent importance given to fluidic ...

EPFL2013

Optofluidic differential spectroscopy for absorbance detection of sub-nanolitre liquid samples

Wuzhou Song, Jianhang Yang

We present a novel optofluidic differential method for carrying out absorbance spectroscopy of subnanolitre volumes of liquid samples on a microfluidic chip. Due to the reduction of liquid volume, the absorbance detection in microfluidics is often hindered ...

Royal Society of Chemistry2012

Droplet-based Liquid-Liquid Extraction and On-Chip IR-Waveguide-Spectroscopy Detection of Cocaine in Human Saliva

Hans Peter Herzig, Peter Van der Wal, Lubos Hvozdara, Philip Wägli, Yu-Chi Chang

We present a portable microsystem to quantitatively detect cocaine in human saliva. The chip combines a simple microfluidic method for multiphase liquid-liquid extraction to transfer cocaine from IR-light absorbing saliva to an IRtransparent solvent with t ...

2012

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