Publication

Epigenetic transmission of the impact of early stress across generations

Publications associées (43)

Adolescent Stress-Induced Ventral Hippocampus Redox Dysregulation Underlies Behavioral Deficits and Excitatory/Inhibitory Imbalance Related to Schizophrenia

Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen, Thamyris Silva

Background and hypothesis: Redox dysregulation has been proposed as a convergent point of childhood trauma and the emergence of psychiatric disorders, such as schizophrenia (SCZ). A critical region particularly vulnerable to environmental insults during ad ...

2024

Cannabis use, cannabis use disorder and mental health disorders among pregnant and postpartum women in the US: A nationally representative study

Aaron Leor Sarvet

Background: Cannabis use and cannabis use disorder (CUD) are associated with mental health disorders, however the extent of this matter among pregnant and recently postpartum (e.g., new moms) women in the US is un-known. Associations between cannabis use, ...

2023

Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response

Maria del Carmen Sandi Perez, Dogukan Hazar Ülgen, Thamyris Silva

Adolescent individuals exhibit great variability in cortical dynamics and behavioral outcomes. The developing adolescent brain is highly sensitive to social experiences and environmental insults, influencing how personality traits emerge. A distinct patter ...

2023

Glucocorticoid-based pharmacotherapies preventing PTSD

Maria del Carmen Sandi Perez, Silvia Monari

Posttraumatic stress disorder (PTSD) is a highly disabling psychiatric condition that may arise after exposure to acute and severe trauma. It is a highly prevalent mental disorder worldwide, and the current treatment options for these patients remain limit ...

PERGAMON-ELSEVIER SCIENCE LTD2023

Identification of biopsychological trait markers in functional neurological disorders

Serafeim Loukas

Weber et al. provide evidence in support of a stress-diathesis model of functional neurological disorders. They identify trauma history in the form of emotional neglect as a psychological risk factor, and reduced hippocampus and amygdala volume as a predis ...

OXFORD UNIV PRESS2022

Information Processing Biases: The Effects of Negative Emotional Symptoms on Sampling Pleasant and Unpleasant Information

Steffen Alexander Herff

Although theories of emotion associate negative emotional symptoms with cognitive biases in information processing, they rarely specify the details. Here, we characterize cognitive biases in information processing of pleasant and unpleasant information, an ...

AMER PSYCHOLOGICAL ASSOC2022

Maladaptive emotion regulation traits predict altered corticolimbic recovery from psychosocial stress

Dimitri Nestor Alice Van De Ville

Background: Adaptive recovery from stress promotes healthy cognitive affective functioning, whereas maladaptive recovery is linked to poor psychological outcomes. Neural regions, like the anterior cingulate and hippocampus, play critical roles in psychosoc ...

ELSEVIER2021

Gene replacement therapy provides benefit in an adult mouse model of Leigh syndrome

Johan Auwerx

Mutations in nuclear-encoded mitochondrial genes are responsible for a broad spectrum of disorders among which Leigh syndrome is the most common in infancy. No effective therapies are available for this severe disease mainly because of the limited capabili ...

2020

Reply to comments on "Explicit versus implicit front advancing schemes for the simulation of hydraulic fracture growth" (Int. J. Numer. Anal. Methods Geomech., 2019, 43 (6), 1300-1315)" by Prof. Linkov

Brice Tanguy Alphonse Lecampion, Haseeb Zia

We reply to Prof. Linkov comments on our article entitled "Explicit versus implicit front advancing schemes for the simulation of hydraulic fracture growth" (Int. J. Numer. Anal. Methods Geomech., 2019, 43 (6), 1300-1315). We present additional results ind ...

WILEY2020

Neurobiological links between stress and anxiety

Maria del Carmen Sandi Perez

Stress and anxiety have intertwined behavioral and neural underpinnings. These commonalities are critical for understanding each state, as well as their mutual interactions. Grasping the mechanisms underlying this bidirectional relationship will have major ...

2019

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