The role of energy dissipation of polymeric scaffolds in the mechanobiological modulation of chondrogenic expression
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Injuries to the meniscus are often treated by partial or total meniscectomy, which is known to be associated with detrimental changes in joint function, ultimately increasing the risk of early degenerative joint diseases. Surgical approaches currently in u ...
Stem cell use in bladder tissue engineering is a recently addressed area of investigation that has generated excitement as a novel way to restore and regenerate lost or damaged urinary bladder tissue. The remodelling of smooth muscle plays a significant ro ...
Most tissue engineering approaches include the delivery of reparative cells to a damaged host tissue. Generally these cells are sought to be of a stem cell character since they retain a high potential for proliferation and differentiation into diverse phen ...
Internal strain measurements in cross-ply carbon-epoxy composite plates under dynamic loads are carried out using embedded FBG sensors. The principle of the FBG interrogation is based on intensity demodulation achieved via a Fabry-Perot filter. To account ...
A novel and low-cost passively compliant mechanism is described that can be used with RC servos to actuate legged robots in tasks involving high dynamic loads such as bouncing. Compliance is achieved by combining visco-elastic material and metal parts. Joi ...
Tensegrities are lightweight space reticulated structures composed of cables and struts. Stability is provided by the self-stress state between tensioned and compressed elements. Tensegrity systems have in general low structural damping, leading to challen ...
Nowadays, cartilage repair is a worldwide centre of interest due to the low potential of cartilage to heal spontaneously and the increasing number of patients around the world. One of the techniques to treat cartilage defect is to use autologous human seru ...
Articular cartilage plays important roles in weight-bearing, lubrication, and load distribution in articulating joints. The tissue is mostly extracellular matrix (>90% by volume) that is synthesized and remodeled by cells (chondrocytes) embedded within. Ad ...
The formation of scar tissue due to dedifferentiation of smooth muscle cells (SMCs) is one of the major issues faced when engineering bladder tissue. Furthermore, cell sources for regenerating the SMC layer are also limiting. Here we explore if human mesen ...
Tissue-specific stem cells found in adult tissues can participate to the repair process following injury. However adult tissues, such as articular cartilage and intervertebral disc, have low regeneration capacity, whereas fetal tissues, such as articular c ...