Publication
Clinical LIF pharmacokinetic measurements with Photofrin II for optimizing the photodetection of early cancer
Publications associées (35)
Time-Dependent Diffusion MRI in Cancer: Tissue Modeling and Applications
In diffusion weighted imaging (DWI), the apparent diffusion coefficient (ADC) has been recognized as a useful and sensitive surrogate for cell density, paving the way for non-invasive tumor staging, and characterization of treatment efficacy in cancer. How ...
Frontiers Research Foundation2017Label-free nanoplasmonic sensing of tumor-associate autoantibodies for early diagnosis of colorectal cancer
Colorectal cancer is treatable and curable when detected at early stages. However there is a lack of less invasive and more specific screening and diagnosis methods which would facilitate its prompt identification. Blood circulating autoantibodies which ar ...
Elsevier Science Bv2016TIE-2-expressing monocytes are lymphangiogenic and associate specifically with lymphatics of human breast cancer
George Coukos, Nicolas Jean Philippe Guex, Luc Henry, Ioannis Xenarios, Hans-Anton Lehr, Nathalie Rufer, Emanuela Marina Iancu
In experimental mouse models of cancer, increasingly compelling evidence point toward a contribution of tumor associated macrophages (TAM) to tumor lymphangiogenesis. Corresponding experimental observations in human cancer remain scarce although lymphatic ...
Taylor & Francis Inc2016Nanosensors for early cancer detection and for therapeutic drug monitoring
The use of nanotechnology for drug delivery in cancer therapy has raised high expectations. Additionally, the use of nanomaterials in sensors to extract and detect tumor specific biomarkers, circulating tumor cells, or extracellular vesicles shed by the tu ...
Future Medicine2015Functionalization of Nanoparticles for Targeted Cancer Imaging and Diagnosis
Solène Marcelle Françoise Marie Passemard
At present time, cancer is the leading cause of death in developed countries. The medical imaging tools currently used in clinics such as radiology, nuclear magnetic resonance imaging, microscopy and endoscopy are not able to reach the sensitivity necessar ...
EPFL2014MicroRNA-mediated control of macrophages and its implications for cancer
Michele De Palma, Mario Leonardo Squadrito, Martin Etzrodt
Deregulation of microRNAs (miRNAs) can drive oncogenesis, tumor progression, and metastasis by acting cell-autonomously in cancer cells. However, solid tumors are also infiltrated by large amounts of non-neoplastic stromal cells, including macrophages, whi ...
Elsevier Sci Ltd2013The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities
Michele De Palma, Douglas Hanahan
It is a time of great promise and expectation for the applications of knowledge about mechanisms of cancer toward more effective and enduring therapies for human disease. Conceptualizations such as the hallmarks of cancer are providing an organizing princi ...
2012Detecting small lung tumors in mouse models by refractive-index microradiology
Refractive-index (phase-contrast) radiology was able to detect lung tumors less than 1 mm in live mice. Significant micromorphology differences were observed in the microradiographs between normal, inflamed, and lung cancer tissues. This was made possible ...
Springer Verlag2011Protein-binding microarray technology and ChIP-sequencing for the identification of novel targets of the human tumor suppressor AP2[alpha]
The mis-regulation of gene transcription in the living cell can be the cause of complex human diseases like cancer. One challenge of the post-genomic era of biomedical research is the development of in vitro techniques for the rapid and cost-effective anal ...
EPFL2009Morphological study of early-stage lung cancer using synchrotron radiation
In the present study the feasibility of applying synchrotron radiation to the morphological study of early-stage lung cancer has been investigated. Lewis lung cancer was implanted and grown in a nude mouse for different periods, and imaged using phase-cont ...
International Union of Crystallography2008