Publication

DprE1-from the Discovery to the Promising Tuberculosis Drug Target

Publications associées (33)

Impact of substrate clogging on vertical connectivity

Giovanni De Cesare, Romain Maxime Dubuis, Robin Schroff

Connectivity between the hyporheic zone and the flow is essential for the development of benthos and the reproductive success of spawning fish. The infiltration of fine sediment leads to clogging of the riverbed, reducing porosity and vertical water exchan ...

2023

Challenges for biophysical modeling of microstructure

Ileana Ozana Jelescu

The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25 years. In this review, we dwell on the various challenges along the journey of bringing a biophysical model from initial design to clinical implementation, identifyi ...

2020

Innovative Tools and in vivo Methods for Tuberculosis Drug Discovery and Development

Raphael Christopher Sommer

Worldwide, tuberculosis (TB) is the leading cause of death due to a single infectious agent, claiming 1.6 million human lives and causing >10 million new cases in 2017 alone, mostly in low-income regions. The intracellular pathogen Mycobacterium tuberculos ...

EPFL2019

Experiments in digital publishing: creating a digital compendium

Matteo Romanello

This chapter introduces the readers and users to the goals of the digitally provided index of the compendium Structures of Epic Poetry and the methods used for it. It also expands on the broader applicability of digital methods in view of electronic publis ...

De Gruyter2019

Chapter 13: Training and Development Needs for a 21st Century Academic

Roland John Tormey, Siara Ruth Isaac, Cécile Hardebolle, Ingrid Le Duc

Broughan, Christine, Graham Steventon, and Lynn Clouder, eds. Global Perspectives on Teaching Excellence: A new era for higher education. Routledge, 2018. ...

Taylor & Francis Ltd2018

Design and development of a display device for Lippmann plates

Kjell Sverre Høyvik Bergum

Semester project to design and develop a display device for use at Musée de l’Elysée to display Lippmann plates. Display platform and light fixtures designed to obtain the full spectrum of Lippmann plates. ...

2018

Open Innovation for Development: An Educative and Entrepreneurial Project between Shenzhen and Addis Ababa

Monique Stéphanie Bolli

Creative and innovative communities, hubs, clusters and industries are supporting and fostering exchange and innovation. China is often perceived as a model for innovation and economic development, countries from the Global South use China as a role model ...

2018

Scientific diasporas, transnationalism and home-country development: evidence from a study of skilled Moldovans abroad

Gabriela Tejada Guerrero

This chapter discusses the Moldovan scientific diaspora made up of students, researchers and those engaged in Professional activities abroad, and their propensity to either return or engage in home-country development initiatives. Moldova has suffered a si ...

Routledge2017

Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-beta-D-ribose 2 '-oxidase

Stewart Cole, Florence Pojer, Joao Pedro De Almeida Neres, Anirban Ghosh

We report the discovery of benzothiazoles, a novel anti-mycobacterial series, identified from a whole cell based screening campaign. Benzothiazoles exert their bactericidal activity against Mycobacterium tuberculosis (Mtb) through potent inhibition of deca ...

Elsevier2015

The Future of Soft Loans as an Instrument of Development Finance: an Assessment

Livia Bianca Fritz

Within the framework of the Post-2015 Development Agenda, discussions on Financing for Development and the future of ODA have intensified recently. Amongst the many financial instruments that are potentially under review, are soft loans. Combining tied aid ...

OEFSE2014

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