Publication

Robust synchronization of coupled circadian and cell cycle oscillators in single mammalian cells

Publications associées (54)

Earth rotation around its axis imposes a 24-hour rhythmicity to all life on the planet.Rather than passively responding to these periodic changes, nature has given us an internal timekeeper, the circadian clock, to anticipate to our advantage the fluctuati ...

EPFL2023

Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia

Jean-Louis Scartezzini

Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we report first findings that exposure to brighter light during daytime may support the immune response to the annual ...

ELSEVIER2022

Comment on "Circadian rhythms in the absence of the clock gene Bmal1"

Felix Naef, Cédric Gobet

Ray et al. (Reports, 14 February 2020, p. 800) recently claimed temperature-compensated, free-running mRNA oscillations in Bmal1(-/-) liver slices and skin fibroblasts. We reanalyzed these data and found far fewer reproducible mRNA oscillations in this gen ...

2021

Human circadian rhythms and urban density: celebrating the natural day-night cycle

Marilyne Andersen, Mark Pauly, Florin Isvoranu, Megan Nicole Danell, Javier Fernandez Contreras

Our exposure to light has a key role in regulating our biological clock through a dedicated photoreceptor present in the human eye. Increased awareness to its criticality when it comes to human well-being is urgently needed, as this criticality is potentia ...

SoomeenHahm Design Ltd2021

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Video Abstract Video Abstract: Theory of time delayed genetic oscillations with external noisy regulation We present a general theory of noisy genetic oscillators with externally regulated production rate and multiplicative noise. The observables that char ...

IOP PUBLISHING LTD2021

Modeling synchronization in globally coupled oscillatory systems using model order reduction

Jan Sickmann Hesthaven, Niccolo' Discacciati

We construct reduced order models for two classes of globally coupled multi-component oscillatory systems, selected as prototype models that exhibit synchronization. These are the Kuramoto model, considered both in its original formulation and with a suita ...

AIP Publishing2021

Enhancing daily light exposure increases the antibody response to influenza vaccination in patients with dementia

Jean-Louis Scartezzini, Mirjam Münch

Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we tested whether a greater long-term daily light exposure supports the immune response to the annual influenza vaccin ...

Cold Spring Harbor Laboratory Press2020

Dealing with Daily Rhythms: Families’ Strategies to Tackle Chronic Time Pressure

Vincent Kaufmann, Guillaume Simon Joseph Drevon, Philippe Gerber

As suggested by the conservation of resources theory, in contemporary societies time is considered as a limited resource in the same way as money and energy. In the current paper, a novel daily rhythm approach related to motility is presented, in order to ...

2020

Low-dimensional dynamics of two coupled biological oscillators

Felix Naef, Eric Paquet, Colas Noé Droin

The circadian clock and the cell cycle are two biological oscillatory processes that coexist within individual cells. These two oscillators were found to interact, which can lead to their synchronization. Here, we develop a method to identify a low-dimensi ...

NATURE PUBLISHING GROUP2019

Tissue-specific circadian transcriptional regulation

Jake Yeung

Circadian rhythms in physiology and behavior evolved to resonate with daily cycles in the external environment. In mammals, organs orchestrate temporal physiology over the 24-hour day, which requires extensive gene expression rhythms targeted to the right ...

EPFL2019

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