Publications associées à Stochastic noise in translation

Improved Cell-Free Transcription-Translation Reactions in Microfluidic Chemostats Augmented with Hydrogel Membranes for Continuous Small Molecule Dialysis

Sebastian Maerkl, Laura Sophie Grasemann, Barbora Lavickova

Increasing the protein production capacity of the PURE cell-free transcription-translation (TX-TL) system will be key to implementing complex synthetic biological circuits, and to establishing a fully self-regenerating system as a basis for the development ...

AMER CHEMICAL SOC2022

Ribo-DT: An automated pipeline for inferring codon dwell times from ribosome profiling data

Felix Naef, Cédric Gobet

Protein synthesis is an energy consuming process characterised as a pivotal and highly regulated step in gene expression. The net protein output is dictated by a combination of translation initiation, elongation and termination rates that have remained dif ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Organohalide respiration: breakthrough towards the elucidation of the electron-accepting moiety of the respiratory chain

Christof Holliger, Julien Maillard, Adrian Schmid, Lorenzo Cimmino

Background Organohalide respiration (OHR) is a bacterial anaerobic process in which chlorinated compound, e.g. tetrachloroethene (PCE), is used as terminal electron acceptors. Dehalobacter restrictus PER-K23, a paradigmatic organohalide-respiring bacterium ...

2021

Control Theory Concepts for Modeling Uncertainty in Enzyme Kinetics of Biochemical Networks

Vassily Hatzimanikatis, Ljubisa Miskovic, Georgios Savoglidis, Milenko Tokic

Analysis of the dynamic and steady-state properties of biochemical networks hinges on information about the parameters of enzyme kinetics. The lack of experimental data characterizing enzyme activities and kinetics along with the associated uncertainties i ...

2019

Single Live Cell Monitoring of Protein Turnover Reveals Intercellular Variability and Cell-Cycle Dependence of Degradation Rates

Felix Naef, David Michael Suter, Eric Paquet, Andrea Brigitta Alber, Martina Biserni

Cells need to reliably control their proteome composition to maintain homeostasis and regulate growth. How protein synthesis and degradation interplay to control protein expression levels remains unclear. Here, we combined a tandem fluorescent timer and pu ...

CELL PRESS2018

Delineating the Mechanism of Ionic Liquids in the Synthesis of Quinazoline-2,4(1H,3H)-dione from 2-Aminobenzonitrile and CO2

Paul Joseph Dyson, Gabor Laurenczy, Martin Hulla, Shoubhik Das, Sami Manoubi Armand Chamam

Ionic liquids (ILs) are versatile solvents and catalysts for the synthesis of quinazoline-2,4-dione from 2-aminobenzonitrile and CO2. However, the role of the IL in this reaction is poorly understood. Consequently, we investigated this reaction and showed ...

Wiley-Blackwell2017

Global Identification of Kinetic Parameters via the Extent-based Incremental Approach

Dominique Bonvin, Julien Léo Billeter, Diogo Filipe Mateus Rodrigues

The identification of reaction kinetics represents the main challenge in building models for reaction systems. The identification task can be performed via either simultaneous model identification (SMI) or incremental model identification (IMI), the latter ...

2017

Rate Law Analysis of Water Oxidation and Hole Scavenging on a BiVO4 Photoanode

Florian Le Formal, Yimeng Ma

Spectroelectrochemical studies employing pulsed LED irradiation are used to investigate the kinetics of water oxidation on undoped dense bismuth vanadate (BiVO4) photoanodes under conditions of photoelectrochemical water oxidation and compare to those obta ...

Amer Chemical Soc2016

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Stochastic noise in translation

Improved Cell-Free Transcription-Translation Reactions in Microfluidic Chemostats Augmented with Hydrogel Membranes for Continuous Small Molecule Dialysis

Ribo-DT: An automated pipeline for inferring codon dwell times from ribosome profiling data

Organohalide respiration: breakthrough towards the elucidation of the electron-accepting moiety of the respiratory chain

Control Theory Concepts for Modeling Uncertainty in Enzyme Kinetics of Biochemical Networks

Circadian clock- and feeding-dependent regulation of translation initiation and elongation in the liver

Single Live Cell Monitoring of Protein Turnover Reveals Intercellular Variability and Cell-Cycle Dependence of Degradation Rates

Computational methods and modeling of cellular function for the optimization of protein production and the study of cellular disease states

Delineating the Mechanism of Ionic Liquids in the Synthesis of Quinazoline-2,4(1H,3H)-dione from 2-Aminobenzonitrile and CO2

Global Identification of Kinetic Parameters via the Extent-based Incremental Approach

Rate Law Analysis of Water Oxidation and Hole Scavenging on a BiVO4 Photoanode

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Chattez avec Graph Search

Improved Cell-Free Transcription-Translation Reactions in Microfluidic Chemostats Augmented with Hydrogel Membranes for Continuous Small Molecule Dialysis

Ribo-DT: An automated pipeline for inferring codon dwell times from ribosome profiling data

Single Live Cell Monitoring of Protein Turnover Reveals Intercellular Variability and Cell-Cycle Dependence of Degradation Rates

Delineating the Mechanism of Ionic Liquids in the Synthesis of Quinazoline-2,4(1H,3H)-dione from 2-Aminobenzonitrile and CO2

Control Theory Concepts for Modeling Uncertainty in Enzyme Kinetics of Biochemical Networks

Computational methods and modeling of cellular function for the optimization of protein production and the study of cellular disease states

Global Identification of Kinetic Parameters via the Extent-based Incremental Approach

Organohalide respiration: breakthrough towards the elucidation of the electron-accepting moiety of the respiratory chain

Circadian clock- and feeding-dependent regulation of translation initiation and elongation in the liver

Rate Law Analysis of Water Oxidation and Hole Scavenging on a BiVO4 Photoanode