Time-domain algorithm for single-photon laser-Doppler flowmetry at large interoptode spacing in human bone
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Over the last decade, bone marrow (BM) adipose tissue (BMAT) has emerged as a distinct adipose depot with unique metabolic properties and effects both in homeostasis and in the progression of disease.We provide a first comprehensive review of existing an ...
Inhibiting thrombosis without generating bleeding risks is a major challenge in medicine. A promising solution may be the inhibition of coagulation factor XII (FXII), because its knock-out or inhibition in animals reduced thrombosis without causing abnorma ...
Several approaches to combine bone substitutes with biomolecules, cells or mechanical loading have been explored as an alternative to the limitation and risk-related bone auto- and allo-grafts. In particular, human bone progenitor cells seeded in porous po ...
Excessive interfacial micromotion endangers the implant primary stability by favoring the formation of a fibrous tissue layer at the bone-implant interface. It was recently proposed that implant micromotion induces fluid flow in the granulation tissue that ...
Bone defects generate a worldwide high demand for bone repair and reconstruction. The incidence of bone defect repair in our aging society is expected to increase in the next decades. As bone auto- and allografting solutions often suffer from limited suppl ...
Due to conservative design models and safe construction practices, infrastructure often has significant yet-unknown reserve capacity that greatly exceeds code requirements. Reserve-capacity assessments lead to better asset-management decisions through eith ...
A sensor is a device that detects or measures a physical property and records, indicates, or otherwise responds to it. In other words, a sensor allows us to interact with the surrounding environment, by measuring qualitatively or quantitatively a given phe ...
Background Venous thromboembolism (VTE) is a complex multifactorial disease influenced by genetic and environmental risk factors. An example for the latter is the regular use of combined oral contraceptives (CC), which increases the risk to develop VTE by ...
Background: orthopaedic surgeons often face clinical situations where improved screw holding power in cancellous bone is needed. Injectable calcium phosphate cements are one option to enhance fixation. Methods: paired screw pullout tests were undertaken in ...
While it has always been true that measurements are made to guide decision-making, there is abundant evidence that not all measurement results are meaningful. We give examples of fully-functional, tested and trusted measurement systems producing nonsensica ...