Detection of Farnesyltransferase Interface Hot Spots through Computational Alanine Scanning Mutagenesis
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Structural engineers play an increasing role in ensuring the transition towards a more sustainable construction sector: a) they are responsible for the design of the most resource- and energy-intensive part of buildings and infrastructure, and b) they regu ...
Over recent years there has been a growing interest in the building frequency analysis for earthquake and structural engineering fields using ambient vibrations. Simultaneously, velocity measurements with LASER remote sensing techniques have gained more in ...
The HIV-1 Rev protein is responsible for shuttling partially spliced and unspliced viral mRNA out of the nucleus. This is a crucial step in the HIV-1 lifecycle, thus making Rev an attractive target for the design of anti-HIV drugs. Despite its importance, ...
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The objective of this study was to unravel the structural properties responsible for the partitioning of solutes in o‐nitrophenyl octyl ether (o‐NPOE)/H2O, a new solvent system for the determination of the partition coefficients of ions. A set of 88 compou ...
The cyclic AMP-dependent transcriptional regulator GlxR from Corynebacterium glutamicum is a member of the super-family of CRP/FNR (cyclic AMP receptor protein/fumarate and nitrate reduction regulator) transcriptional regulators that play central roles in ...
Objective Mephedrone has been recently made illegal in Europe, but little empirical evidence is available on its impact on human cognitive functions. We investigated acute and chronic effects of mephedrone consumption on drug-sensitive cognitive measures, ...