Red and NIR light dosimetry in the human deep brain
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Hydrocephalus is a cerebral disease where brain ventricles enlarge and compress the brain parenchyma towards the skull leading to symptoms like dementia, walking disorder and incontinence. The origin of normal pressure hydrocephalus is still obscure. In or ...
This thesis work aims to optimize the treatment of hydrocephalus. It consists of two distinct objectives: the optimization of the diagnosis of patients implanted with a shunt system for the derivation of cerebro-spinal fluid (CSF) and the optimization of t ...
Two methods for measuring the optical properties of tissue, i.e. reduced scattering and absorption coefficient, were developed. The first one was designed for in vitro investigations. It is based on the measurement of the spatially resolved transmittance t ...
The aim of this principally experimental study is to understand from fluid mechanic principles why an insignificant anesthetic dose administered as a short bolus into the cerebrospinal fluid inside the subarachnoid space provides greater pain relief than a ...
Objects Deep brain stimulation (DBS) has turned out to be the surgical technique of choice for the treatment of movement disorders, e.g. Parkinsons disease (PD), the usual target being the subthalamic nucleus (STN). The targeting of such a small structure ...
Neuronavigation systems are usually subject to inaccuracy due to intraoperative changes like brain shift or tumor resection. In order to correct for these deformations a biomechanical model of the brain is proposed. Not only elastic tissues, but also fluid ...
