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PACCMIT/PACCMIT-CDS: identifying microRNA targets in 3′ UTRs and coding sequences

Publications associées (40)

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Similarities and differences of polyadenylation signals in human and fly

Felix Naef, Philipp Bucher

ABSTRACT: BACKGROUND: Cleavage of messenger RNA (mRNA) precursors is an essential step in mRNA maturation. The signal recognized by the cleavage enzyme complex has been characterized as an A rich region upstream of the cleavage site containing a motif with ...

2006

Structure of PTB Bound to RNA: Specific Binding and Implications for Splicing Regulation

Luc Reymond, Philipp Wenter

The polypyrimidine tract binding protein (PTB) is a 58-kDa RNA binding protein involved in multiple aspects of mRNA metab., including the repression of alternative exons. We have detd. the soln. structures of the four RNA binding domains (RBDs) of PTB, eac ...

2005

Motivation: MicroRNAs (miRNAs) are small endogenous RNAs that can play important regulatory roles via the RNA-interference pathway by targeting mRNAs for cleavage or translational repression. We propose a computational method to predict mi ...

Oxford University Press2005

Prediction of Regulatory Modules Comprising MicroRNAs and Target Genes

Giovanni De Micheli

Motivation: MicroRNAs are small endogenous RNAs that can play important regulatory roles via the RNA-interference pathway by targeting mRNAs for cleavage or translational repression. We propose a computational method to predict miRNA regulatory modules or ...

2005

Cosadoca, Consortium de sauvetage du patrimoine documentaire en cas de catastrophe : un site web pour la sauvegarde du patrimoine documentaire

En 2003, trois institutions confrontées aux problèmes posés par la sauvegarde du patrimoine documentaire et situées sur le même site géographique se sont regroupées au sein du Consortium de sauvetage du patrimoine documentaire en cas de catastrophe (COSADO ...

2005

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The absence of benchmarks for Web sites with dynamic content has been a major impediment to research in this area. We describe three benchmarks for evaluating the performance of Web sites with dynamic content. The benchmarks model three common types of dyn ...

2002

Multimedia Teaching on WWW: a New Approach

Murat Kunt, Iva Bogdanova Vandergheynst

The Internet offers new and exciting possibilities for personalized and distance education. The Web Teaching project at ITS is creating the tools needed to provide complete high quality multimedia courses for delivery over the World Wide Web (WWW). Aside f ...

EUSIPCO2002

Post-transcriptional regulation of mRNA translation and stability in iron metabolism involves the interaction between the trans-acting cytoplasmic iron regulatory proteins (IRP-1 and IRP-2) and cis-acting iron-responsive elements (IREs) in mRNA 5'- or 3'-u ...

1999

Automatic Configuration For Remote Diagnosis And Monitoring Of Railway Equipments

Txomin Nieva

Today, there is no standard system for performing maintenance on heterogeneous railway equipments. Maintenance staff needs a standard application capable of diagnosing and monitoring heterogeneous on-board equipments. We propose to build a web-based diagno ...

1999

Real Benefits of Active Caching in the WWW

Andrey Naumenko

We present our research on active caching in the WWW. We drew some key conclusions on the service properties and its significance, according to the results of our analysis of the WWW content. These conclusions include the percentage values of the potential ...

1999