Targeted optogenetic stimulation to study the computational properties in neuronal ensembles recorded by multi-electrode devices
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Understanding how the information is coded in large neuronal networks is one of the major challenges for neuroscience. A possible approach to investigate the information processing capabilities of the neuronal ensembles is given by the use of dissociated n ...
Abstract—Mapping neuronal networks activity of in-vitro cell cultures with microelectrode array (MEA) based systems, providing a spatial resolution down to cellular/sub-cellular levels and an adequate temporal resolution for resolving action potential prop ...
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Since their introduction, Micro-Electrode Arrays (MEAs) have been exploited as devices providing distributed information about learning, memory and information processing in a cultured neuronal network, thus changing the field of view from single cell leve ...
Definition of single spikes from multiunit spike trains plays a critical role in neurophysiology and in neuroengineering as it does the question of how much information is encoded by single neurons in a neuronal network. Moreover, the possibility to develo ...
PhotoMEA is a biosensor useful for the analysis of an in vitro neuronal network, fully based on optical methods. Its function is based on the stimulation of neurons with caged glutamate and the recording of neuronal activity by Voltage-Sensitive fluorescen ...
Since their introduction 30 years ago, Micro-Electrode Arrays (MEAs) have been exploited as devices providing distributed information about learning, memory and information processing in a cultured neuronal network, thus changing the field of view from the ...
The resonant properties of the intrinsic dynamics of single neurons could play a direct role in behaviour. One plausible role is in the recognition of temporal patterns, such as that seen in the auditory communication systems of Orthoptera. Recent behaviou ...
A large number of studies on neuronal physiology and plasticity have provided a detailed picture of the molecular machinery underlying the modulation of neuronal activity. On the contrary, the mechanisms controlling properties of complex neuronal networks ...
Large network monitoring of electrogenic cells by means of micro electrode arrays (MEA) has become a valuable methodology in electrophysiology. In order to understand the mechanisms of learning (plasticity) and memory in fundamental neuroscience it is impe ...
