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Tinnitus is the chronic perception of ringing or other phantom sounds. Some tinnitus patients addi- tionally suffer from loudness hyperacusis that is the over-sensitivity to environmental sounds. Here, we recruited eight patients with unilateral hearing loss and tinnitus, among which four also have loudness hyperacusis. For every patient, the audiogram was acquired by measuring the audible thresholds for 9 frequency presentations in the range 125Hz-8kHz with steps of half an octave. The fMRI data was recorded on a 7T MRI scanner that allows exquisite spatial resolution of 1mm3. The experimental paradigm was according to the tonotopic mapping experiment by (Da Costa et al., 2011), which consists in presenting a sequence of 15 pure frequency tones in 14 cycles (88Hz- 11340Hz). Voxels from the auditory cortex are then extracted and their timecourse is fitted to the sine/cosine with the period of the block-based paradigm, which gives access to the amplitude and the phase of the response. Voxels are labeled using the relationship between the phase and the presented frequency, and then amplitudes of voxels with same label are averaged resulting into 15 fMRI features/subject. We then use partial least-squares correlation (PLSC; Krishnan et al., 2011) to establish the link between the audiogram measures and the fMRI tonotopy responses. By max- imizing correlation in a multivariate way, PLSC identifies a set of latent variables (LVs) that each contain an fMRI saliency vector and two audiogram saliency vectors (one for each group; i.e., hy- peracusis and non-hyperacusis). Using permutation testing, we found evidence for a single LV being significant (p
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