Electrokinetic and Optical Control of Bacterial Microrobots
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This work investigates the influence of diffusion adaptation on the behavior of networks of micro-organisms that are subject to Brownian fluctuations in the motion of their constituent agents. The organisms are assumed to share information, usually through ...
For such biomedical applications as single cell manipulation and targeted delivery of chemicals, it is important to fabricate microstructures that can be powered and controlled without a tether in fluidic environments. In this work, we describe the constru ...
Lanthanide bioprobes and bioconjugates are ideal luminescent stains in view of their low propensity to photobleaching, sharp emission lines and long excited state lifetimes permitting time-resolved detection for enhanced sensitivity. We show here how the i ...
Exposure of an isogenic bacterial population to a cidal antibiotic typically fails to eliminate a small fraction of refractory cells. Historically, fractional killing has been attributed to infrequently dividing or nondividing "persisters." Using microflui ...
With the objective of understanding the role of size and current level of filamentary regions on the resistive switching parameters, detailed conductive atomic force microscope investigations of resistive memory cells having different dimensions have been ...
The formation and maintenance of boundaries between neighbouring groups of embryonic cells is vital for development because groups of cells with distinct functions must often be kept physically separated. Furthermore, because cells at the boundary often ta ...
We present a microrobotic platform that combines MEMS-based capacitive force sensing technology, a dual-stage positioning system and a real-time control and acquisition architecture with computer vision automation to manipulate and mechanically characteriz ...
Transport of individual cells or chemical payloads on a subcellular scale is an enabling tool for the study of cellular communication, cell migration, and other localized phenomena. We present a magnetically actuated robotic system for the fully automated ...
Regenerative medicine aims to recreate functional tissues in vitro for the regeneration of damaged organs and solve the dramatic problem of transplant rejection. Cornea integrity is primordial for our vision. Several therapies to regenerate healthy corneal ...
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause late-onset Parkinson's disease (PD). Emerging evidence suggests a role for LRRK2 in the endocytic pathway. Here, we show that LRRK2 is released in extracellular microvesicles (i.e. exosomes) ...