Publication
Synthesis of Alkynylated Heterocycles by Direct C-H Alkynylation or Domino Alkynylation Reactions
Concepts associés (42)
Environmental impact of fashion
The fashion industry, particularly manufacture and use of apparel and footwear, is a significant driver of greenhouse gas emissions and plastic pollution. The rapid growth of fast fashion has led to around 80 billion items of clothing being consumed annually, with a large number going to landfill. Less than one percent of clothing is recycled to make new clothes. The industry produces an estimated 10% of all greenhouse gas emissions.
Ring-closing metathesis
Ring-closing metathesis (RCM) is a widely used variation of olefin metathesis in organic chemistry for the synthesis of various unsaturated rings via the intramolecular metathesis of two terminal alkenes, which forms the cycloalkene as the E- or Z- isomers and volatile ethylene. The most commonly synthesized ring sizes are between 5-7 atoms; however, reported syntheses include 45- up to 90- membered macroheterocycles. These reactions are metal-catalyzed and proceed through a metallacyclobutane intermediate.