Evolution and characterization of MS2 bacteriophage and echovirus 11 Resistance to disinfection by CLO2

In this study, we investigate if frequent exposure to disinfectants promotes the emergence of virus resistance to disinfectants. We found that repeated passages causes viruses gain increasing resistance toward ClO2. However, the role of ClO2 is not clear in the emergence of the resistance. Therefore we suggest that water disinfection should be optimized in order to prevent the emergence and potential proliferation of resistant viruses.