Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function
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As a part of 2016 Physionet/CinC callenge, this work aims at the detection of abnormal phonocardiogram (PCG) recordings. Heart sound signal analysis has been an active research topic over the past decades with various studies such as heart sound segmentati ...
Cardiac and skeletal muscle function relies on a continuous energy production via fatty acid metabolism and mitochondrial oxidation of pyruvate, with a fine balance between substrate delivery and utilization. Changes in metabolism are increasingly being im ...
The efficient azidation of beta-keto esters and silyl enol ethers using a benziodoxole-derived azide transfer reagent is reported. The azidation of cyclic beta-keto esters could be achieved in up to quantitative yields in the absence of any catalyst. In th ...
Numerical modeling of the human cardiovascular system (CVS) represents an active branch of research which allows the medical specialists to advance in understanding of underlined processes of blood circulation and the heart work at any scale, moreover, it ...
Kinetic modeling of PET data derived from mouse models remains hampered by the technical inaccessibility of an accurate input function (IF). In this work, we tested the feasibility of IF measurement with an arteriovenous shunt and a coincidence counter in ...
In the developing heart, a subset of endothelial cells (ECs) undergo a process of endothelial to mesenchymal transformation (EMT) that leads to the remodeling of the cardiac cushions and the formation of the cardiac valves. Understanding how microenvironme ...
Premature babies are not fully equipped to deal with the outside world. Their immature bodies make them highly at risk to a large number of physiological complications. Therefore, while they are still immature, premature babies are taken care of in neonato ...
Barth syndrome is an X-linked genetic disorder caused by mutations in the tafazzin (taz) gene and characterized by dilated cardiomyopathy, exercise intolerance, chronic fatigue, delayed growth, and neutropenia. Tafazzin is a mitochondrial transacylase requ ...
The potential of imaging photoplethysmography for cardiovascular monitoring applications has been demonstrated recently. Various processing schemes have been proposed to extract heart rate (HR) from a defined region of interest (ROI) on the face. However, ...
In a bilingual paper entitled 'Bibliometrics as weapons of mass citation - La bibliometrie comme arme de citation massive',([1]) recently translated into English,([2]) we have argued that the current fashion of ranking people, papers and journals is anythi ...
