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Disposable orbitally shaken TubeSpin bioreactor 600 for Sf9 cell cultivation in suspension
Publications associées (32)
Primary data for EPFL thesis "Characterisation of conditional alleles of the Schizosaccharomyces pombe cytokinesis regulator byr4"
Regulation of cytokinesis is essential for the cell during its division cycle. Failure to do so can lead to aneuploidy, which can be fatal and lead to senescence or cancer. A useful model organism for studying cytokinesis in eukaryotes is Schizosaccharomyc ...
EPFL Infoscience2023Characterisation of conditional alleles of the Schizosaccharomyces pombe cytokinesis regulator byr4
Regulation of cytokinesis is essential for the cell during its division cycle. Failure to do so can lead to aneuploidy, which can be fatal and lead to senescence or cancer. A useful model organism for studying cytokinesis in eukaryotes is Schizosaccharomyc ...
EPFL2023Intrinsically High Capacity of Animal Cells From a Symbiotic Cnidarian to Deal With Pro-Oxidative Conditions
The cnidarian-dinoflagellate symbiosis is a mutualistic intracellular association based on the photosynthetic activity of the endosymbiont. This relationship involves significant constraints and requires co-evolution processes, such as an extensive capacit ...
FRONTIERS MEDIA SA2022Engineering Agrobacterium tumefaciens Adhesion to Target Cells
Alexandre Louis André Persat, Xavier Jean-Yves Pierrat, Jeremy Pak Hei Wong, Alix Kim Lan Pham
Agrobacterium tumefaciens is a plant pathogen commonly repurposed for genetic modification of crops. Despite its versatility, it remains inefficient at transferring DNA to many hosts, including to animal cells. Like many pathogens, physical contact between ...
AMER CHEMICAL SOC2022Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel
Pierre Gönczy, Georgios Hatzopoulos
Centrioles are eukaryotic organelles that template the formation of cilia and flagella, as well as organize the microtubule network and the mitotic spindle in animal cells. Centrioles have proximal-distal polarity and a 9 fold radial symmetry imparted by a ...
CELL PRESS2022Fluorogenic probes for live-cell imaging
The development of novel fluorogenic probes and their use in live-cell imaging lead to a plethora of discoveries in biological research. Herein I report on novel red fluorogenic probes for live-cell super-resolution microscopy of various cellular organelle ...
EPFL2020Integrative approach to analyze the proximal region of the Trichonympha agilis centriole
The centrosome, the major microtubule organizing center in animal cells, is composed of two orthogonally arranged centrioles and surrounding pericentriolar material. Centrioles are evolutionary conserved organelles characterized by a nine-fold symmetry of ...
EPFL2018A comparison of orbitally-shaken and stirred-tank bioreactors: pH modulation and bioreactor type affect CHO cell growth and protein glycosylation
Florian Maria Wurm, David Hacker, Lucia Baldi Unser, Marc Moniatte, Dominique Terry Monteil Jr, Valentin Juvet
Orbitally shaken bioreactors (OSRs) support the suspension cultivation of animal cells at volumetric scales up to 200 L and are a potential alternative to stirred-tank bioreactors (STRs) due to their rapid and homogeneous mixing and high oxygen transfer ra ...
American Chemical Society2016Chemical Genetic Screen Identifies Natural Products that Modulate Centriole Number
Kai Johnsson, Pierre Gönczy, Michele Graciotti, Zhou Fang
Centrioles are microtubule-based organelles found in most eukaryotic cells and that are critical for the formation of cilia and flagella, as well as of centrosomes in animal cells. The number of centrioles must be strictly regulated in proliferating cells ...
Wiley-Blackwell2016Protrusion-retraction switches and traction forces in spontaneous cell polarization
Cell migration is a fundamental property of all animal cells which is involved in processes such as embryogenesis, immune response, tissue regeneration and cancer metastasis. Directional migration requires cell polarization which could happen in response t ...
EPFL2016