Mechanical and Functional Study of Cell Physiology at the Nanoscale
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The phenotypic diversity of breast cancer has been proposed to result from different target cell types undergoing oncogenic transformation and giving rise to cancer stem cells. Global gene expression profiling revealed distinct molecular phenotypes and som ...
Nowadays the mechanism regulating the corneal epithelium renewal still remains unclear. Until now it was thought to be the fact of stem cells distributed in the limbus, generating TA cells migrating towards the central cornea and responsible for its renewa ...
Maintenance of the blood system is dependent on dormant haematopoietic stem cells (HSCs) with long-term self-renewal capacity. After injury these cells are induced to proliferate to quickly reestablish homeostasis(1). The signalling molecules promoting the ...
A series of homoditopic ligands H2LCX (X=4–6) has been designed to self-assemble with lanthanide ions (LnIII), resulting in neutral bimetallic helicates of overall composition [Ln2ACHTUNGTRENUNG(LCX)3] with the aim of testing the influence of substituents ...
Alginate gel formation on-chip is presented in the first part of this thesis. The technique allows immobilization, and release, of biological cells on-chip. Furthermore, via layer by layer deposition, a locally heterogeneous environment can be generated at ...
Cornea functions as an outermost lens and plays an important role in vision. For cornea diagnosis and treatment, a microscopic imaging system with cellular resolution and high eye safety is strongly desired. Recently, the cell morphology of corneal epithel ...
The Nano-Tera.CH initiative is a broad engineering program in Switzerland for health and security of humans and the environment, currently funded by the Swiss government. The program rationale is rooted in advances in engineering nano-scale materials and t ...
Performance degradation data obtained on single solid oxide fuel cells tested at 850°C with air and humidified H2 and using Ni-YSZ anode supported cells are presented. Microscopic investigation is carried out on both anode and cathode to quantify variation ...
During tissue development, cells are able to form different layers and to self organize. At the moment, there are two principal hypotheses that try to explain cell sorting. The so called differential adhesion hypothesis (DAH) posits that cells organize acc ...
Most tissue engineering approaches include the delivery of reparative cells to a damaged host tissue. Generally these cells are sought to be of a stem cell character since they retain a high potential for proliferation and differentiation into diverse phen ...
